Results 71 to 80 of about 92,257 (303)

Splenic lymphangiomas as a common indication for splenectomy: a case series with literature review

BMC Surgery, 2022
Background Splenic lymphangiomas (SL) are very rare benign cystic lesions found in pediatric population. Their occurrence in adults is exceptional. Splenectomy is the common management of splenic lesions for diagnostic and/or therapeutic purpose. Our aim
Boubacar Efared, Aïchatou Balaraba Abani Bako, Hama Younssa, Idrissa Boubacar, Aliou Zabeirou, Hamadou Halidou Koura, Habiba Salifou Boureima, Soumaila Amadou, Idrissa Seriba Coulibaly, James Didier Lassey, Hassan Nouhou   +10 more
doaj   +1 more source

Coeliac disease, splenic function, and malignancy [PDF]

Gut, 1982
Blood films from 41 cases of coeliac disease complicated by malignancy were examined and evidence of hyposplenism found in 12 cases (29%). This is similar to the proportion of adult coeliacs without malignancy who have hypoplenism and it is concluded that impaired splenic function is not associated with the development of malignancy in coeliac disease.
D A, Robertson, C M, Swinson, R, Hall, M S, Losowsky   +3 more
openaire   +2 more sources

Clinical relevance of circulating and splenic immature myeloid cells in pancreatic diseases. [PDF]

, 2011
Context Blood and spleen expansion of immature myeloid cells might compromise the immune response to cancer, enabling tumor outgrowth and metastasis. Objective To study the pattern of circulating and splenic lymphocyte subsets and immature myeloid cells ...
MOZ, STEFANIA, Rossi E, Tamburrino D, PLEBANI, MARIO, Fogar P, De Franchis G, ZAMBON, CARLO-FEDERICO, Falconi M, GRECO, ELIANA, Pedrazzoli S, PADOAN, ANDREA, Pelloso M, Pederzoli P, Navaglia F, Fadi E, BASSO, DANIELA, SPERTI, COSIMO, BOZZATO, DANIA   +17 more
core  

Glucose Deprivation‐Driven Concurrent Induction of Apoptosis/Disulfidptosis/Ferroptosis by Tumor Targeting Nanoassemblies in Triple‐Negative Breast Cancer Therapy

Advanced Functional Materials, EarlyView.
Innovative hybrid nanoassemblies installed with ferrocene, D‐α‐tocopherol succinate, and phloretin exploit the metabolic vulnerability of triple‐negative breast cancer under glucose starvation. By blocking glucose uptake, this single nanoplatform simultaneously orchestrates apoptosis, disulfidptosis, and ferroptosis to achieve synergistic and ...
Song Yi Lee, ChaeRim Hwang, Seong Eun Kim, Mrinmoy Karmakar, Seo Jin Jung, Hyeonseok Jang, Hae‐In Kim, Heejung Yang, Junmin Lee, Dae‐Duk Kim, Hyun‐Jong Cho   +10 more
wiley   +1 more source

Diffuse Calcifications of the Spleen in a Woman with Systemic Lupus Erythematosus

Case Reports in Medicine, 2015
Systemic lupus erythematosus (SLE) is a multisystemic autoimmune disease, which affects a wide variety of organs including the spleen. Splenic involvement in SLE includes conditions such as splenomegaly, hyposplenism, infarction, and spontaneous rupture.
Aristeides G. Vaiopoulos, Meletios A. Kanakis, Kyriaki Katsouri, Stavroula Kyriazi, George A. Vaiopoulos, Phaedon Kaklamanis   +5 more
doaj   +1 more source

Affinity‐Tuned Albumin Hitchhiking Extends the Bioorthogonal Capture Window in Pretargeting Radiotheranostics

Advanced Healthcare Materials, EarlyView.
Pharmacokinetic engineering of clickable radioligands was achieved via albumin hitchhiking approach within a pretargeted radiotheranostics delivery platform. This approach reduced rapid renal elimination, expanded bioorthogonal capture window, boosted tumor uptake by ∼3.5‐fold, and improved the tumor‐to‐liver ratio by ∼6‐fold.
Xie He, Nicholas L. Fletcher, Gayathri R. Ediriweera, Yifei Zhu, James Humphries, Christopher B. Howard, Jiazheng Wang, Craig A. Bell, Kristian Kempe, Kristofer J. Thurecht   +9 more
wiley   +1 more source

Splenic epithelial cysts and splenomegaly: diagnosis and management [PDF]

, 1998
Splenomegaly is a common problem. in the absence of systemic illness or malignancy splenic cysts must be considered, especially the epithelial variety. For large cysts total splenectomy has long been recommended.
Halma, C, Hulzebos, CV, de Vries, TW, Leemans, R   +3 more
core   +1 more source

Gardiquimod Nanoemulsion Targets Cutaneous Leishmaniasis Lesions Reducing Systemic Toxicity and Parasite Burden

Advanced Healthcare Materials, EarlyView.
Nanoemulsion delivery of a TLR7 agonist enhances safety and promotes colocalization with Leishmania‐infected macrophages in skin lesions, enabling a ∼2‐log reduction in parasite burden. However, tissue‐level constraints and TLR‐driven regulatory feedback generate a mixed immune response that limits complete parasite clearance.
Carmen Palomino‐Cano, M. Carmen Mera‐Delgado, Esther Moreno, Esther Larrea, Lecnia Aguirre, Jonathan Miguel Zanatta, Sónia Barros‐Carvalho, Iola F. Duarte, Ricardo Silvestre, Juan M. Irache, Javier Carrión, Socorro Espuelas   +11 more
wiley   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Infarto esplénico asociado a infección por citomegalovirus, primer reporte de caso en Colombia

Infectio, 2020
Introduction: Splenic infarction occurs when the splenic artery or any of its branches are occluded, either by distant emboli or by thrombosis in situ.
Santiago Sánchez-Pardo
doaj   +1 more source