Results 11 to 20 of about 434,859 (340)

Splenic Infarction in Patients with Philadelphia-negative Myeloproliferative Neoplasms

open access: yesInternal Medicine, 2022
Objective We retrospectively analyzed the prevalence and clinical features of splenic infarctions in patients with Philadelphia chromosome-negative myeloproliferative neoplasms (Ph- MPNs). Patients Patients diagnosed with essential thrombocythemia (ET), polycythemia vera (PV), prefibrotic/early primary myelofibrosis (pre-PMF), or PMF from January 1996 ...
Lee, Myung-Won   +8 more
openaire   +3 more sources

Thalidomide Reduces Vascular Endothelial Growth Factor Immunostaining in Canine Splenic Hemangiosarcoma

open access: yesVeterinary Sciences, 2020
Hemangiosarcomas (HSA) are common neoplasms of dogs that often metastasize and are typically fatal. Recently it was demonstrated that thalidomide extends the survival time of dogs with HSA, potentially due to thalidomide-induced inhibition of vascular ...
Jonathan P. Bray, John S. Munday
doaj   +2 more sources

Clinical and biological features of B‐cell neoplasms with CDK6 translocations: an association with a subgroup of splenic marginal zone lymphomas displaying frequent CD5 expression, prolymphocytic cells, and TP53 abnormalities

open access: yesBritish Journal of Haematology, 2020
A translocation involving the cyclin‐dependent kinase 6 (CDK6) gene [t(CDK6)] is a rare but recurrent abnormality in B‐cell neoplasms. To further characterise this aberration, we studied 57 cases; the largest series reported to date. Fluorescence in situ
B. Gailllard   +28 more
semanticscholar   +1 more source

Atraumatic Spontaneous Splenic Rupture With Unknown Etiology

open access: yesCureus, 2023
Splenic rupture of all causes is a potentially life-threatening event for patients. The infrequency of atraumatic splenic rupture (ASR) poses a significant diagnostic challenge due to atypical findings.
Humberto Perez   +2 more
semanticscholar   +1 more source

TGF-β signaling in myeloproliferative neoplasms contributes to myelofibrosis without disrupting the hematopoietic niche

open access: yesJournal of Clinical Investigation, 2022
Myeloproliferative neoplasms (MPNs) are associated with significant alterations in the bone marrow microenvironment that include decreased expression of key niche factors and myelofibrosis. Here, we explored the contribution of TGF-β to these alterations
Juo-Chin Yao   +8 more
semanticscholar   +1 more source

Splenic artery embolization for treatment of portal hypertension due to essential thrombocythemia

open access: yesPortal Hypertension & Cirrhosis, 2022
Philadelphia‐negative myeloproliferative neoplasms (MPNs) are significantly associated with the development of splanchnic vein thrombosis, which leads to portal hypertension.
Jiacheng Liu, Xiaoming Liu, Bin Xiong
doaj   +1 more source

Inflammatory pseudotumor of the spleen

open access: yesHematology Reports, 2015
Isolated splenic inflammatory pseudotumors (IPT) are extremely rare, typically benign, inflammatory lesions with varied clinical presentations that pose a diagnostic challenge to clinicians due to their similarity in appearance to neoplasms.
Georgia McMahon   +2 more
doaj   +1 more source

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