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Differentiating Benign from Malignant Causes of Splenomegaly: Is Acoustic Radiation Force Impulse Elastography Helpful? [PDF]
Purpose: To evaluate the ability of acoustic radiation force impulse (ARFI) elastography in differentiating benign from malignant etiologies of splenomegaly based on differences in splenic stiffness.
Alhyari A+6 more
europepmc +2 more sources
Radiotherapy for massive, symptomatic splenomegaly has been used in a palliative setting since the early 1990’s. Massive splenomegaly may be seen in CML, CLL, hairy cell leukemia and splenic marginal zone lymphomas, prolymphocytic leukemia ...
Hemendra Mod+3 more
doaj +3 more sources
Massive splenomegaly, defined as length spleen greater than 20 cm, is a relatively rare entity with a broad differential. Primary splenomegaly occurs in the setting of leukemias and lymphomas, whereas secondary splenomegaly is more common and carries a ...
Meagan Mayo+3 more
doaj +3 more sources
Splenomegaly with Jaundice [PDF]
A. M. Stewart-Wallace, R. A. Rowlands
openalex +4 more sources
Giant spleen as a surgical challenge: Case report and literature review [PDF]
Introduction. According to the guidelines of the European Association of Endoscopic Surgery, any case where the maximum craniocaudal splenic diameter exceeds 20 cm is considered massive splenomegaly.
Erić Dragan+4 more
doaj +1 more source
Rapamycin-filgrastim combination therapy ameliorates portal hypertension-induced splenomegaly: Role of β actin and S100A9 proteins modulation [PDF]
Objective(s): Thioacetamide (TAA) was administered to induce an animal model of liver disease with secondary splenomegaly to assess the mechanisms underlying the effects of rapamycin and filgrastim when taken separately or in combination on the ...
Shaimaa Abdelrahman+2 more
doaj +1 more source
A major genetic locus in Trypanosoma brucei is a determinant of host pathology [PDF]
The progression and variation of pathology during infections can be due to components from both host or pathogen, and/or the interaction between them. The influence of host genetic variation on disease pathology during infections with trypanosomes has ...
A Beckers+55 more
core +12 more sources
Management of Massive Splenomegaly [PDF]
57-year-old man presented with a 3-month history of fatigue, fever and increasing abdominal pain.He had completed treatment for follicular lymphoma and JAK2 positive myeloproliferative disorder 2 months previously. This case demonstrates therapeutic and diagnostic rationale for open splenectomy in, to our knowledge, one of the largest recorded ...
Hudson, Victoria E+2 more
openaire +4 more sources