Results 111 to 120 of about 129,482 (378)

Risk factors for in-hospital mortality of visceral leishmaniasis patients in eastern Uganda. [PDF]

, 2009
OBJECTIVE: To identify risk factors for in-hospital mortality in patients treated for visceral leishmaniasis (VL) in Uganda. METHODS: Retrospective analysis of VL patients' clinical data collected for project monitoring by Médecins Sans Frontières in ...
Bern, Bryceson, Chappuis, Collin, Croft, Delgado, Desjeux, Guerin, Jamjoom, Lyons, Moore, Mueller, Mueller, Olliaro, Ritmeijer, Ritmeijer, Seaman, Sundar, Thakur, Veeken, WHO   +20 more
core   +3 more sources

Expert Perspectives on a Clinical Challenge: Hematologic Malignancies and Vasculitis

Arthritis &Rheumatology, Accepted Article.
Systemic vasculitis describes a collection of rare diseases each caused by inflammation of blood vessel walls that can cause severe systemic complications [[3, 4]](#ref‐0003). The pattern of vascular inflammation and resultant damage is frequently variable and may be mimicked, or directly triggered, by infection or malignancy.
Michelle L. Robinette, Hetty E. Carraway
wiley   +1 more source

Splenic infarction: an update on William Osler\u27s observations. [PDF]

, 2010
BACKGROUND: Osler taught that splenic infarction presents with left upper abdominal quadrant pain, tenderness and swelling accompanied by a peritoneal friction rub.
Aharoni, MD, Dvora, Berlowitz, MB BCh, Daniel, Breuer, MD, Gabriel S, Hain, MD, Daniel, Lawrence, MA MBBS MRCP, Yaacov R, Pokroy, MB BCh, Russell   +5 more
core   +1 more source

A mutation in caspase-9 decreases the expression of BAFFR and ICOS in patients with immunodeficiency and lymphoproliferation [PDF]

, 2015
Lymphocyte apoptosis is mainly induced by either death receptor-dependent activation of caspase-8 or mitochondria-dependent activation of caspase-9. Mutations in caspase-8 lead to autoimmunity/lymphoproliferation and immunodeficiency. This work describes
Boggio, E, Cappellano, G, Chiocchetti, A., Clemente, N, Dianzani, C, Dianzani, I, Dianzani, U, Gigliotti, Cl, Notarangelo, Ld, Orilieri, E, Pignata, C, Quinti, Isabella, Ramenghi, U, Santoro, C, Toth, E, Valletti, Pa   +15 more
core   +2 more sources

MPL mutations and palpable splenomegaly are independent risk factors for fibrotic progression in essential thrombocythemia

Blood Cancer Journal, 2016
MPL mutations and palpable splenomegaly are independent risk factors for fibrotic progression in essential ...
M. Haider, Y. Elala, N. Gangat, C. Hanson, A. Tefferi   +4 more
semanticscholar   +1 more source

BCR::ABL1‐Positive Acute Myeloid Leukemia

American Journal of Hematology, EarlyView.
Alban Canali, Jean‐Baptiste Rieu, Leopoldine Lapierre, Barbara J. Bain   +3 more
wiley   +1 more source

Enhancing antitumor immunity through the combination of cholesterolized TLR7 agonist liposomes and radiotherapy: a role for IL‐1β and the inflammasome pathway

Cancer Communications, EarlyView.
Abstract Background Radiotherapy (RT) is a key treatment modality in cancer therapy, utilizing high‐energy radiation to directly kill tumor cells. Recent research has increasingly highlighted RT's potential to indirectly enhance antitumor immunity. However, this immune activation alone often fails to generate sustained systemic antitumor responses.
Xuejiao Han, Yuan Cheng, Dandan Wan, Aqu Alu, Ziqi Zhang, Zhenfei Bi, Manni Wang, Yan Tang, Weiqi Hong, Siyuan Chen, Li Chen, Yuquan Wei   +11 more
wiley   +1 more source

Treponema denticola in Disseminating Endodontic Infections [PDF]

, 2006
Treponema denticola is a consensus periodontal pathogen that has recently been associated with endodontic pathology. In this study, the effect of mono-infection of the dental pulp with T.
Foschi, F., Izard, Jacques, Müller, R., Prati, C., Sambri, V., Sasaki, H., Stashenko, P.   +6 more
core   +2 more sources

Rapamycin Attenuates Splenomegaly in both Intrahepatic and Prehepatic Portal Hypertensive Rats by Blocking mTOR Signaling Pathway

PLoS ONE, 2016
Background Spleen enlargement is often detected in patients with liver cirrhosis, but the precise pathogenetic mechanisms behind the phenomenon have not been clearly elucidated.
Yunyang Chen, Weijie Wang, Huakai Wang, Yongjian Li, Minmin Shi, Hongwei Li, Jiqi Yan   +6 more
semanticscholar   +1 more source

Adversarial Synthesis Learning Enables Segmentation Without Target Modality Ground Truth [PDF]

arXiv, 2017
A lack of generalizability is one key limitation of deep learning based segmentation. Typically, one manually labels new training images when segmenting organs in different imaging modalities or segmenting abnormal organs from distinct disease cohorts.
arxiv