Results 121 to 130 of about 129,482 (378)

Efficacy of hepatic transplantation in patients with primary sclerosing cholangitis [PDF]

, 1993
Controlled trials to assess the therapeutic benefit of orthotopic hepatic transplantation (OHTx) for primary sclerosing cholangitis (PSC) cannot be justified in view of improvement of patient survival after this operation since 1981.
Abu-Elmagd, KM, Demetris, AJ, Dickson, ER, Fung, JJ, Krom, RAF, Langworthy, AL, Malinchoc, M, Murtaugh, PA, Starzl, TE, Van Thiel, DH   +9 more
core  

Spleen histology in children with sickle cell disease and hereditary spherocytosis: Hints on the disease pathophysiology [PDF]

, 2016
open2Hereditary spherocytosis (HS) and sickle cell disease (SCD) are associated with splenomegaly and spleen dysfunction in pediatric patients. Scant data exist on possible correlations between spleen morphology and function in HS and SCD.
Alaggio Rita, Colombatti Raffaella, De Vito Rita, Fuligni Fabio, Gamba Piergiorgio, Ichino Martina, Pizzi Marco, Sabattini Elena, Sainati Laura, Santoro Luisa, Zucchetta Pietro   +10 more
core   +1 more source

Splenomegaly and Its Associations with Genetic Polymorphisms and Treatment Outcome in Colorectal Cancer Patients Treated with Adjuvant FOLFOX

Cancer research and treatment : official journal of Korean Cancer Association, 2016
Purpose Splenomegaly is a clinical surrogate of oxaliplatin-induced sinusoidal obstruction syndrome (SOS). We investigated development of splenomegaly and its association with treatment outcome and genetic polymorphisms following adjuvant 5-fluorouracil,
Mi-Jung Kim, Sae-Won Han, Dae-Won Lee, Y. Cha, Kyung-Hun Lee, Tae-Yong Kim, D. Oh, Se Hyung Kim, S. Im, Y. Bang, Tae-You Kim   +10 more
semanticscholar   +1 more source

Antileishmanial Activities of Carvacrol Nanoencapsulate in Biopolymeric Nanoparticles

Chemistry &Biodiversity, Accepted Article.
Visceral leishmaniasis (VL) is a neglected parasitic disease, and the first‐line treatments for VL include drugs that exhibit serious toxicological issues. In this sense, new molecules are sought for VL treatment, such as Carvacrol (Car), a phenolic monoterpene that has shown strong activity against Leishmania spp.
Joyce Cordeiro Borges, Anne Beatriz Cunha Barros, Leonardo Lima Cardoso, Tatjana de Lima Souza Keesen, Luís André de Almeida Campos, Isabella Macário Ferro Cavalcanti, Elisângela Afonso de Moura Kretzschmar   +6 more
wiley   +1 more source

RomA, A Periplasmic Protein Involved in the Synthesis of the Lipopolysaccharide, Tunes Down the Inflammatory Response Triggered by Brucella [PDF]

, 2018
Brucellaceae are stealthy pathogens with the ability to survive and replicate in the host in the context of a strong immune response. This capacity relies on several virulence factors that are able to modulate the immune system and in their structural ...
Altabe, Silvia Graciela, Casabuono, Adriana Cristina, Cassataro, Juliana, Couto, Alicia Susana, Czibener, Cecilia, Fulgenzi, Fabiana Rosa, Guaimas, Francisco Fernando, Pasquevich, Karina Alejandra, Spera, Juan Manuel, Ugalde, Juan Esteban, Valguarnera, Pablo Ezequiel   +10 more
core   +1 more source

Short-term administration of JAK2 inhibitors reduces splenomegaly in mouse models of β-thalassemia intermedia and major

Haematologica, 2017
b-thalassemia is one of the most common congenital red blood cell (RBC) disorders characterized by limited bglobin synthesis and ineffective erythropoiesis. Based on the requirements for blood transfusion, the disease can be classified as non-transfusion
C. Casu, Vania Lo Presti, Paraskevi Rea Oikonomidou, L. Melchiori, O. Abdulmalik, P. Ramos, S. Rivella   +6 more
semanticscholar   +1 more source

Ethnomedicinal uses, phytochemistry, pharmacological activities, and toxicology of the subfamily Gomphrenoideae (Amaranthaceae): A comprehensive review

Chemistry &Biodiversity, Accepted Article.
The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its promising ...
Dayanna Isabel Araque Gelves, Giulia Cristina Andreoli de Souza, Alvaro Jose Hernandez Tasco, Marcos Jose Salvador   +3 more
wiley   +1 more source

The hyper-reactive malarial splenomegaly: a systematic review of the literature

Malaria Journal, 2015
The hyper-reactive malarial splenomegaly syndrome (HMS) is a leading cause of massive splenomegaly in malaria-endemic countries. HMS is caused by a chronic antigenic stimulation derived from the malaria parasite. Classic Fakunle’s major criteria for case
S. Leoni, D. Buonfrate, A. Angheben, F. Gobbi, Z. Bisoffi   +4 more
semanticscholar   +1 more source

Trends and Outcomes Following Percutaneous Coronary Intervention in Patients With Myeloproliferative Neoplasms: Insights From National Database

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Myeloproliferative neoplasms (MPN) are associated with an increased cardiovascular risk including acute coronary syndrome. However, there is a lack of comprehensive data regarding the rate of percutaneous coronary intervention (PCI), as well as the in‐hospital characteristics and outcomes for MPN patients.
Song Peng Ang, Jia Ee Chia, Chayakrit Krittanawong, Robert N. Piana, Kwan Lee, Chadi Ayoub, JR Exequiel Pineda, David Song, Debabrata Mukherjee   +8 more
wiley   +1 more source

A Rare Case of Hemophagocytic Lymphohistiocytosis of Unknown Etiology [PDF]

, 2017
Hemophagocytic lymphohistiocytosis (HLH) is an uncommon cytokine storm syndrome marked which can cause high mortality. In adults, acquired HLH usually has an underlying infectious, autoimmune or malignant process that triggers the syndrome.
Damsker, Jason A., Friedenheim, Richard, Gagnon, Marie Helene, Micaily, Ida   +3 more
core   +1 more source