Results 21 to 30 of about 129,482 (378)
In primary myelofibrosis, extra-domain A fibronectin (EDA-FN), the result of alternative splicing of FN gene, sustains megakaryocyte proliferation and confers a pro-inflammatory phenotype to bone marrow cell niches. In this work we assessed the levels of
Alessandro Malara+6 more
doaj +1 more source
Incidentally Detected Celiac Disease with Splenomegaly on 18F FDG PET/CT: A Potential Lymphoma Mimic [PDF]
Celiac disease is an immune-mediated disorder triggered by hypersensitivity to gluten occurring in genetically susceptible individuals. A high-index of suspicion is needed for diagnosis as patients can be asymptomatic or present with atypical symptoms or
Ananya Panda+5 more
doaj +1 more source
COVID-19: Chest Computed Tomography Imaging Patterns in Assessment of Disease Progression and Severity [PDF]
Introduction: Chest Computed Tomography (CT) plays an important role in the diagnosis and management of Corona Virus Disease (COVID-19) infection.
Sachin Thammegowda+4 more
doaj +1 more source
Splenomegaly in the tropics. [PDF]
Philip D. Marsden, P. J. Hamilton
openalex +4 more sources
Clinical overview on RASopathies
Abstract RASopathies comprise a group of clinically overlapping developmental disorders caused by genetic variations affecting components or modulators of the RAS‐MAPK signaling cascade, which lead to dysregulation of signal flow through this pathway.
Martin Zenker
wiley +1 more source
Predominant Role of Immunoglobulin G in the Pathogenesis of Splenomegaly in Murine Lupus
Systemic lupus erythematosus (SLE) is characterized by high levels of autoantibodies and multiorgan tissue damage. The pathogenesis of splenomegaly in SLE remains unknown. In this study, the role of immunoglobulin G (IgG) generation and deposition in the
Qian Zhang+5 more
semanticscholar +1 more source
Background Left‐sided portal hypertension (LSPH) caused by splenic vein (SV) division in pancreaticoduodenectomy (PD) with portal vein (PV) resection remains challenging. The current study aimed to investigate the efficacy of splenic artery (SA) ligation
Kazuyuki Gyoten+9 more
doaj +1 more source
Prediction of esophagogastric varices associated with oxaliplatin administration
Background Oxaliplatin is a key drug for the chemotherapy of colorectal cancer; however, it is also known to cause non‐cirrhotic portal hypertension. We aimed to identify the characteristics of patients who developed esophagogastric varices (EGVs) after ...
Yosuke Satta+18 more
doaj +1 more source
PRIMARY BILIARY CHOLANGITIS DIAGNOSIS IN A SERONEGATIVE 19-YEAR-OLD WOMAN [PDF]
Primary biliary cholangitis (PBC) is an autoimmune disease that destroys small bile ducts, culminating in liver failure. It typically affects middle-aged, Caucasian women. Most cases have detectable antimitochondrial antibodies.
Sara Santos
doaj +1 more source
Co-Inheritance of Haemoglobin D-Punjab and Beta Thalassemia - A Rare Variant [PDF]
Haemoglobinopathies are a frequent cause of anaemia in Northwestern India due to traditional practices of consanguineous marriages. Haemoglobin D-Punjab is one of the most common subvariants (55%) of haemoglobin D, which can be inherited as a homozygous
Kalyan Mansukhbhai Shekhda+4 more
doaj +1 more source