Results 141 to 150 of about 94,284 (293)

Completion vs. early discontinuation of chemotherapy and the impact on 5‐year all‐cause mortality in women treated for early‐stage breast cancer from 2015 to 2020: A cohort study using a target trial emulation approach

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Chemotherapy is given for early‐stage breast cancer; however, some patients discontinue before completing all planned cycles. This study investigated the impact of early chemotherapy discontinuation on treatment outcomes. Methods This retrospective cohort study used a target trial emulation framework to conduct a causal analysis of the all‐
Luke Steventon, Chengsheng Ju, Kenneth K. C. Man, Rebecca Roylance, Diego Ottaviani, Chiara Creed, Michal Sladkowski, Alec Wisner, Li Wei, Pinkie Chambers   +9 more
wiley   +1 more source

Legendre-tau approximation for functional differential equations. Part 2: The linear quadratic optimal control problem [PDF]

The numerical scheme based on the Legendre-tau approximation is proposed to approximate the feedback solution to the linear quadratic optimal control problem for hereditary differential systems. The convergence property is established using Trotter ideas.
Ito, K., Teglas, R.
core   +1 more source

Convex Approximation by Quadratic Splines

Journal of Approximation Theory, 1993
The author estimates the error of approximation by \(C^ 1\)-convex quadratic splines of a given convex function \(f\) without any smoothness requirements on its derivative in terms of \(\omega_ 3(f,{1 \over n})\). Actually, he proves the following main Theorem: Let \(f \in C[0,1]\) be a convex, and \(n\) a positive integer.
openaire   +2 more sources

On the Prediction of pDNA Productivity Across Diverse Bioprocesses Using Ensemble Hybrid Models

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The global demand for plasmid DNA (pDNA) is rapidly increasing due to its key role in the manufacture of mRNA vaccines and advanced therapy medicinal products (ATMPs). However, the reliance on suboptimal batch and/or fed‐batch processes, as well as the diversity and increasing complexity of plasmid constructs pose significant challenges during
Nikolaos Stratis, Massimo Morbidelli, Alexandros Kiparissides   +2 more
wiley   +1 more source

On the Sensitivity of the Parameters of the Intensity-Based Stochastic Model for Terrestrial Laser Scanner. Case Study: B-Spline Approximation. [PDF]

Sensors (Basel), 2018
Kermarrec G, Alkhatib H, Neumann I.
europepmc   +1 more source

Impact of Agitation Power Input on Aspergillus oryzae Metabolism: Application of Multi‐Omics on an Industrial Enzyme Fermentation

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The agitation power input substantially impacts the oxygen transfer rate in aerobic fermentation processes. Furthermore, in a carbon‐limited process where the substrate feed rate is controlled by the concentration of dissolved oxygen, the power input will consequently govern the feed rate.
Mariana Albino, Jean‐Marie Mouillon, Gisela Nadal‐Rey, Carina L. Gargalo, Ulrich Krühne, Krist V. Gernaey, Mads O. Albæk   +6 more
wiley   +1 more source

Difference equation state approximations for nonlinear hereditary control problems [PDF]

Discrete approximation schemes for the solution of nonlinear hereditary control problems are constructed. The methods involve approximation by a sequence of optimal control problems in which the original infinite dimensional state equation has been ...
Rosen, I. G.
core   +1 more source

Lifespan Pancreas Morphology for Control Versus Type 2 Diabetes Using AI on Largescale Clinical Imaging

Clinical Anatomy, EarlyView.
ABSTRACT Understanding how pancreas size and shape change with normal aging is critical for establishing a baseline to detect deviations in type 2 diabetes and other pancreatic disease. We measure pancreas size and shape using morphological measurements from early development through aging (ages 0–90).
Lucas W. Remedios, Chloe Cho, Trent M. Schwartz, Dingjie Su, Gaurav Rudravaram, Chenyu Gao, Aravind R. Krishnan, Adam M. Saunders, Michael E. Kim, Shunxing Bao, Thomas A. Lasko, Alvin C. Powers, Bennett A. Landman, John Virostko   +13 more
wiley   +1 more source

A novel stochastic ten non-polynomial cubic splines method for heat equations with noise term

Partial Differential Equations in Applied Mathematics
In this paper, a new numerical method for solving a class of stochastic partial differential equations is presented. The proposed method is based on a non-polynomial cubic spline algorithm with an O(h4) local truncation error.
Aisha F. Fareed, Ahmed G. Khattab, Mourad S. Semary   +2 more
doaj   +1 more source

Synergistic Effects of Normal‐Range Serum Sodium and Potassium on Mortality: The Modifying Role of Inflammation From a NHANES Cohort Analysis

Chronic Diseases and Translational Medicine, EarlyView.
Nonlinear associations of serum sodium levels with cardiovascular (A) and all‐cause mortality (B)among 32,837 adults. Nonlinear associations of serum potassium levels with cardiovascular (C) and all‐cause mortality (D) among 32,837 adults. ABSTRACT Background This study aimed to investigate the associations of serum sodium and potassium levels within ...
Haofeng Zhang, Fudong He, Zhenger Fang, Guangjun Zheng, Biying Zhou, Xia Chen, Mingliang Liu, Guang Hao   +7 more
wiley   +1 more source