Results 91 to 100 of about 170,536 (269)
Kinesin‐Induced Buckling Reveals the Limits of Microtubule Self‐Repair
Advanced Science, EarlyView.This study shows that kinesin‐driven buckling induces extensive microtubule lattice damage that often exceeds intrinsic self‐repair and leads to filament failure. While curvature, motor motility, and force individually cause limited damage, their combination overwhelms repair.
Shweta Nandakumar +9 more
wiley +1 more source
AerospaceThe Thin-Plate Splines (TPS) technique, using Kybic et al.’s generalized interpolation approach, is extended to differentiable manifolds. The initial application to surface mesh deformation resulting from parameterized Computer Aided Design (CAD) used in
Gilbert Rogé, Ludovic Martin
doaj +1 more source
O dvou flexibilních metodách pro dvourozměrnou regresní analýzu [PDF]
ACC Journal, 2012 Práce je věnována neparametrickému statistickému modelování dvourozměrných ploch na základě pozorovaných dat, tj. dvourozměrně regresni analýze. Model je konstruován jako kombinace jednoduchých bázových funkcí, jako jsou spliny, gaussiány apod. Nevýhodou
Petr Volf
doaj
Graellsia, 2003 Se evalúa la capacidad de modelos de interpolación de tres familias: superficies de tendencias, regresiones multiples con predictores derivados de un modelo digital del elevaciones (MDE) y kriging, para interpolar la temperatura en España peninsular. Los
J. Bustamante
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Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy
Advanced Science, EarlyView.Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu +4 more
wiley +1 more source
Parametric Surfaces for Elliptic and Hyperbolic Geometries
MathematicsBackground/Objectives: In computer graphics, virtual worlds are constructed and visualized through algorithmic processes. These environments are typically populated with objects defined by mathematical models, traditionally based on Euclidean geometry ...
László Szirmay-Kalos +3 more
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Erasable FAP Targeted Spray‐On Probe for Fluorescence‐Guided Surgery
Advanced Science, EarlyView.We present the first erasable spray‐on probe for fluorescence‐guided surgery. Following topical delivery, FAP‐FLASH550 targets fibroblast activation protein–expressing stromal cells, delineating tumor margins with high tumor‐to‐background ratios. A 365 nm UV light pulse rapidly erases fluorescent signals through triazene photodegradation and subsequent
Zachary Rabinowitz +2 more
wiley +1 more source
The Instability in the Dimensions of Polynomial Splines of Mixed Smoothness over T-Meshes
MathematicsMixed-smoothness splines facilitate localized control over smoothness; however, the issue of dimensional instability in mixed-smoothness spline spaces remains unstudied in the existing literature.
Pengxiao Wang
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Annals of Gastroenterological Surgery, EarlyView.We retrospectively analyzed clinical data from patients who underwent hepatectomy for hepatocellular carcinoma (HCC) using LCA‐based grading system. These findings provide a new risk stratification framework for the design of precision surgery to treat patients with HCC.
Ling Liu +5 more
wiley +1 more source