Results 41 to 50 of about 621,908 (253)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

D-OPTIMAL DESIGNS FOR SPLIT-PLOT MIXTURE PROCESS VARIABLE DESIGNS OF THE STEEL SLAG EXPERIMENT

open access: yesBarekeng, 2022
The nature of the steel slag concrete experiment followed a mixture process variable (MPV) design. In this study, the concrete is composed of five mixture components, cement, fine aggregate, coarse aggregate, percentage steel slag replaced the fine ...
Faula Arina   +3 more
doaj   +1 more source

Multiple Comparisons in Split Block and Split-Split Plot Designs [PDF]

open access: yes, 1991
16 pages, 1 article*Multiple Comparisons in Split Block and Split-Split Plot Designs* (Federer, Walter T.; McCulloch, Charles E.) 16 ...
Federer, Walter T.   +4 more
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

THE INFLUENCE OF AMMONIUM NITRATE AND POTASSIUM HUMATE ON CHEMICAL COMPOSITION OF CALENDULA OFFICINALIS, L. PLANT UNDER TWO TYPES OF SOIL CONDITIONS [PDF]

open access: yesFayoum Journal of Agricultural Research and Development, 2019
An experiment was conducted during 2015/2016 and 2016/2017 growingseasons at the Experimental Farm of Faculty of Agriculture, FayoumUniversity, Fayoum.
Wesam A. Badran   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The Misunderstood Split Plot [PDF]

open access: yes, 1974
36 pages, 1 article*The Misunderstood Split Plot* (Federer, W.
Cornell University. Dept. of Biological Statistics and Computational Biology.   +3 more
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Reducing the number of experiments in split-plot optimization designs

open access: yesJournal of the Brazilian Chemical Society, 2004
Two experiment reduction procedures for split-plot designs are investigated using a data set containing 160 experiments, consisting of 80 duplicate results for the optimization of a water-acetone-N,N-dimethylformamide mixture with HCl, o-dianisidine and ...
Bortoloti João A.   +2 more
doaj  

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