Results 31 to 40 of about 10,156,002 (281)
Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin +17 more
wiley +1 more source
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono +7 more
wiley +1 more source
Background Energy-based surgical scalpels are designed to efficiently transect and seal blood vessels using thermal energy to promote protein denaturation and coagulation. Assessment and design improvement of ultrasonic scalpel performance relies on both
Pinnell Margaret F +2 more
doaj +1 more source
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
THE INFLUENCE OF AMMONIUM NITRATE AND POTASSIUM HUMATE ON CHEMICAL COMPOSITION OF CALENDULA OFFICINALIS, L. PLANT UNDER TWO TYPES OF SOIL CONDITIONS [PDF]
An experiment was conducted during 2015/2016 and 2016/2017 growingseasons at the Experimental Farm of Faculty of Agriculture, FayoumUniversity, Fayoum.
Wesam A. Badran +3 more
doaj +1 more source
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito +7 more
wiley +1 more source
Brachiaria physiological parameters in agroforestry systems
: This study aimed to assess the effects of Eucalyptus and maize shading on characteristics related to water use by Brachiaria in agroforestry systems.
Márcia Vitória Santos +6 more
doaj +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
The Waterlogging Tolerance of Wheat Varieties in Western of Turkey
This research was conducted to determine the wheat varieties against waterlogging which was clearly increased in recent years. For this purpose, this study was performed at Field Crops and Soil Science Department of Agricultural Faculty of Adnan Menderes
Ilkay Yavas, Aydin Unay, Mehmet Aydin
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source

