Results 41 to 50 of about 128,422 (258)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Lab-Scale Fiber Spinning Experimental Design Cost Comparison [PDF]
Journal of Engineered Fibers and Fabrics, 2010 Many statistical experimental designs are too costlyor require too much raw material to be feasible forlab-scale fiber spinning experiments. In this study afour-factor response surface design is presented tostudy the fiber spinning process in detail at ...
Jeffrey C. Moreland +2 more
doaj
Acta Agriculturae Slovenica, 2017 A sequential cropping system of soybean-lowland (NERICA L-42)-upland (NERICA 2) rice was established at Abeokuta and Ibadan (Nigeria) to evaluate the performance of the cropping system.
Paul Abayomi Sobowale SOREMI +6 more
doaj +1 more source
Journal of Applied Sciences and Environmental Management, 2021 Field experiments were conducted at Yola and Garkida in Adamawa State, North-Eastern Nigeria during the 2017 rainy season. In the Yola location the experiment was conducted at the Teaching and Research Farm of the Department of Crop Production and ...
A.B. Mustapha +3 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Applied SciencesConsiderable effort has been put over the last few decades into clarifying the correct design and analysis of split-plot factorial experiments. However, the information found in the literature is scattered and sometimes still not easy to grasp for non ...
Ioanna Teknetzi +2 more
doaj +1 more source
Gradual correction of phosphorus availability in the no-tillage system
Revista Ceres, 2016 In areas cultivated under no-tillage system, the availability of phosphorus (P) can be raised by means of the gradual corrective fertilization, applying phosphorus into sowing furrows at doses higher than those required by the crops.
Carlos Hissao Kurihara +4 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Sensors, 2017 Eight different types of nanostructured perovskites based on YCoO 3 with different chemical compositions are prepared as gas sensor materials, and they are studied with two target gases NO 2 and CO.
Francesco Bertocci +4 more
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source