Results 61 to 70 of about 345,419 (293)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Optimal Designs For the Restricted Maximum Likelihood Estimators in a Random Split-Plot Model
Lithuanian Journal of Statistics, 2017 The design effect for the restricted maximum likelihood estimators of variance components in acompletely randomized split-plot model is studied. The model was used to represent the response generated froman experimental scenario where the whole-plot and
Oluwole Nuga, G. N. Amahia, Fatai Salami
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Two-Factor Experiments with Split Units Constructed by Cyclic Designs and Square Lattice Designs
Revstat Statistical Journal, 2018 We consider nested row-column designs with split units for a two-factor experiment. The most optimal design in this case is that of using for the whole plots a Latin square while for the subplot treatments with a completely randomized design for each ...
Kazuhiro Ozawa +3 more
doaj +1 more source
International Journal of Nanomanufacturing, 2009 Statistical design of experiments is widely used among scientists and engineers to understand influential factors in a laboratory or manufacturing process.
C. Yuangyai +4 more
semanticscholar +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Acta Agriculturae Slovenica, 2017 Trial was carried out at Federal University of Agriculture, Abeokuta, Nigeria between 2010 and 2012 to determine response of lowland rice-ratooned rice-fluted pumpkin sequence to fertilizer.
Sunday Ojo Adigbo +8 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source