Results 81 to 90 of about 10,156,002 (281)
Optimal Split-Plot Designs [PDF]
, 2002 Split-plot designs are heavily used in industry, especially when factor levels are difficult or costly to change or to control. This is because this type of design avoids too many changes of the whole plot factor levels, which leads to considerable savings in cost and time. The purpose of this chapter on split-plot designs is twofold.
openaire +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Robust product design : Saving trials with split-plot confounding
, 2001 Robust production experimentation is described as an important quality engineering activity. A cake mix experiment performed to illustrate split-plot confounding was used to eliminate the low resolution of standard inner and outer array designs.
Kulahci, Murat,, Bisgaard, Søren,
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ComTech, 2018 This research aimed to provide a theoretical framework for intrinsically nonlinear models with two additive error terms. To achieve this, an iterative Gauss-Newton via Taylor Series expansion procedures for Estimated Generalized Least Square (EGLS ...
Ikwuoche John David +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Effect of planting methods on quantity and quality of sugar beet in saline regions
Majallah-i Chughundar-i Qand, 2014 Water and soil salinity in some regions of Isfahan, East Azerbaijan, and West Azerbaijan provinces and also other parts of Iran are the main hindrance for crop planting.
M.R. Jahadakbar +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Testing for lack of fit in blocked and split-plot response surface designs
Textbooks on response surface methodology emphasize the importance of lack-of-fit tests when fitting response surface models, and stress that, to be able to test for lack of fit, designed experiments should have replication and allow for pure-error ...
Gilmour, Steven G.
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Split-split-plot design for a non-orthogonal experiment with lupine [PDF]
, 2015 W pracy przedstawiono przykład konstrukcji układu niekompletnego split-split-plot (SSP) dla nieortogonalnego doświadczenia trójczynnikowego. Niekompletność układu SSP jest związana z obiektami czynnika trzeciego w kolejności.
Ambroży-Deręgowska, Katarzyna +1 more
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