Results 91 to 100 of about 10,156,002 (281)

Construction of estimation-equivalent second-order split-split-plot designs

, 2011
In many experimental settings, some experimental factors are very hard to change or very expensive to change, some factors are hard to change, and some factors are easy to change, which usually leads to a split-split-plot design.
RAJA, UZMA, University of Alabama. Dept. of Information Systems, Statistics, and Management Science, PERRY, MARCUS B., Yuan, Fang, LEE, JUNSOO, ADAMS, MICHAEL B., CONERLY, MICHAEL D.   +6 more
core   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

PENGARUH VARIETAS, PEROMPESAN DAUN, DAN PENYEMPROTAN FUNGISIDA TERHADAP INTENSITAS PENYAKIT KARAT (Puccinia horiana P. Henn.) PADA TANAMAN KRISAN (Dendranthema grandiflora Tzvelev)

Agric, 2016
Puccinia horiana P. Henn. is the pathogen which caused of white rust on chrysanthemum. It is the most serious disease on chrysanthemum. Study on the effect of varieties, defoliation, and fungicide application against rust diseases (Puccinia horiana) was ...
E Silvia Yusuf, - Suhardi
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

D-optimal design of split-split-plot experiments

In industrial experimentation there is growing interest in studies that span more than one processing step. Convenience often dictates restrictions in randomization in passing from one processing step to another.
GOOS, Peter, BRADLEY, Jones
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Optimal split‐plot orthogonal arrays

, 2018
It is well known that many industrial experiments have split‐plot structures. Compared to completely randomised experiments, split‐plot designs are more economical and thus have received much attention among researchers.
林長鋆, Chang-Yun Lin, Po Yang
core   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

EFFECTS OF ROW SPACING AND SEEDING RATES ON SOME AGRONOMICAL TRAITS OF SPRING CANOLA (BRASSICA NAPUS L.) CULTIVARS [PDF]

Journal of Central European Agriculture, 2009
The objective of the study was to evaluate the effects of row spacing and seeding rates on agronomical traits of three spring canola (Brassica napus L.) cultivars in Iran during 2003-2004. Traits evaluated were plant height, number of seeds pod-1, number
Yazdifar SHAHIN, Ramea VALIOLLAH
doaj  

Effectiveness of blower and HVLS fan in feedlot to performans of brahman, belmont red and charolais cattle

E3S Web of Conferences, 2018
The purpose of this study is to determine the impact of heat stress on Brahman Cross cattle performance which is maintained by feedlot with three treatments (non using fan, blower fan and HVLS fan) using split plot design, Giving the fan is treated as ...
Yasin David Isaac, Tafsin Ma’ruf, Ginting Simon P   +2 more
doaj   +1 more source