Results 61 to 70 of about 149,581 (278)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
‘South Fabricated’: Computing Stories of Global South Insecurity [PDF]
Contexto InternacionalSci-fi tales of computing technologies have been carriers of an unabashed anxiety vis-à-vis the present and the future of politics. In International Relations, these tales split in two: either technology divides developed from developing, while also ...
Luisa Cruz Lobato
doaj +1 more source
Learning to Become an Expert: Deep Networks Applied To Super-Resolution Microscopy
, 2018 With super-resolution optical microscopy, it is now possible to observe molecular interactions in living cells. The obtained images have a very high spatial precision but their overall quality can vary a lot depending on the structure of interest and the
De Koninck, Paul +5 more
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
The Complexity of Phylogeny Constraint Satisfaction Problems
, 2017 We systematically study the computational complexity of a broad class of computational problems in phylogenetic reconstruction. The class contains for example the rooted triple consistency problem, forbidden subtree problems, the quartet consistency ...
Bodirsky, Manuel +2 more
core +1 more source
Partially Dominated Splittings
, 2014 We propose a weak form of domination, called partially dominated splitting and the main result is that there is a partially dominated splitting over a nonsingular compact invariant set for a flow if, and only if, the associated linear Poincare flow has a dominated ...
openaire +2 more sources
The Inverse Split and Non-split Domination in Graphs
International Journal of Computer Applications, 2010 paper, we define the notions of inverse split and non split domination in graphs. We get many bounds on inverse split and non split domination numbers. Nordhaus-Gaddum type results are also obtained for these new parameters.
K. Ameenal Bibi, R. Selvakumar
openaire +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Open MathematicsLet T(X) be a full transformation semigroup on a nonempty set X. The Cayley digraph Γ of a semigroup T(X) with respect to the Green’s L $\mathcal{L}$ -class is a digraph with vertex set T(X) and two vertices α, β ∈ T(X) are adjacent as an arc (α, β ...
Chaiya Yanisa +2 more
doaj +1 more source
Importanza della diversità diatopica nell’insegnamento della lingua spagnola come L2
Lea, 2013 The syncretic cultural identity, in which the Spanish language and its linguistic hegemony are grounded and have reflected its political hegemony, led Spain to take on a predominant role in standardization over the centuries.
Silvia Lafuente
doaj +1 more source