Results 51 to 60 of about 2,529 (166)

Metabolic feature profiling and metabolic vulnerability in acute lymphoblastic leukemia

Interdisciplinary Medicine, EarlyView.
For the first time, our study develops a novel metabolic classification and subtyping program, metabolic reprogramming‐based classifier for acute lymphoblastic leukemia, using internal PDT‐ALL‐2016 and external cohorts, which dissects metabolic profiling, clinical outcome, and therapeutic vulnerability for precision metabolic intervention in ALL ...
Xiaojie Liang, Zihong Cai, Bingqing Tang, Zicong Huang, Baiwei Luo, Bingyu Lin, Yunong Yang, Zhihao Jin, Xiaoqing Li, Xiuli Xu, Yeling Deng, Chaoran Lin, Liang Wang, Hongsheng Zhou   +13 more
wiley   +1 more source

Ultrasound Findings in Symptomatic HADD of the Hand and Wrist. A Case Series of 37 Patients

Journal of Clinical Ultrasound, EarlyView.
Ultrasound enables accurate diagnosis of hydroxyapatite deposition disease of the hand and wrist in patients with acute, non‐traumatic pain, typically in middle‐aged women. Characteristic calcifications, often in the resorptive phase, support diagnosis, while radiography may confirm findings without the need for advanced imaging.
Marco Becciolini, Riccardo Picasso, Antonio Corvino, Federico Zaottini   +3 more
wiley   +1 more source

Navigating Acceptability: A Think‐Aloud Study of Subjective and Contextual Factors in Radiographic Image Rejection

Journal of Medical Radiation Sciences, EarlyView.
This study investigated how radiographers assess radiographic image quality using the think‐aloud technique. It reveals that image quality assessment is shaped by both technical standards and subjective, contextual factors, including patient condition and interprofessional dynamics. This highlights the importance of balancing standardised criteria with
Robin Decoster, Rachel Toomey, Michaela Davis, Marie‐Louise Ryan   +3 more
wiley   +1 more source

Unsupervised phenotyping of the periodontal architecture through high‐dimensional clustering of electronic health records: A multicenter study

Journal of Periodontology, EarlyView.
Abstract Background To identify novel periodontal phenotypes using unsupervised machine learning on a large‐scale, multicenter cohort, specifically characterizing disease patterns based on the “periodontal architecture” of localized structural failures (tooth mobility and molar furcation defects) rather than global severity averages alone. Methods This
Georgios S. Chatzopoulos, Larry F. Wolff
wiley   +1 more source

Sono‐Anatomy and Histology of the Deep Fasciae in the Upper Limb

Journal of Ultrasound in Medicine, EarlyView.
The deep fascia of the upper limb represents a pivotal anatomical structure essential for effective force transmission, dynamic compartmentalization and musculoskeletal stability. Its composition (rich in type I collagen fibers) enables both mechanical resilience and functional adaptability, crucial for the upper limb's complex movements.
Carmelo Pirri, Nina Pirri, Lucia Petrelli, Veronica Macchi, Andrea Porzionato, Raffaele De Caro, Carla Stecco, Levent Özçakar   +7 more
wiley   +1 more source

Accuracy of Key Sonographic Markers for Juxta‐Articular Fractures

Journal of Ultrasound in Medicine, EarlyView.
Objectives To systematically evaluate sonographic features of long bone juxta‐articular fractures and identify key diagnostic predictors using machine learning‐based feature selection. Methods This prospective single‐center diagnostic accuracy study enrolled 121 patients with clinically suspected juxta‐articular fractures.
Xiaofang Fu, Lirong Liu, Hao Sun, Changqin Sun, Qinhan Yang, Mengjie Dou, Duo Shi, Junpu Hu, Zhiming He, Guangquan Zhou, Shiyu Jin, Faqin Lv   +11 more
wiley   +1 more source

The Intraoperative Microlesion Effect Positively Correlates With the Short‐Term Clinical Effect of Deep Brain Stimulation in Parkinson's Disease

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objective During the surgical procedure of deep brain stimulation (DBS), insertion of an electrode in the subthalamic nucleus (STN) frequently causes a temporary improvement of motor symptoms, known as the microlesion effect (MLE). The objective of this study was to determine the correlation between the intraoperative MLE and the clinical ...
Stèfan F. Lange, Naomi I. Kremer, Teus van Laar, Fiete Lange, T. Elien Steendam‐Oldekamp, D. L. Marinus Oterdoom, Anthony R. Absalom, J. Marc C. van Dijk, Gea Drost   +8 more
wiley   +1 more source

Nail Disorders in Systemic Conditions

JEADV Clinical Practice, EarlyView.
ABSTRACT Nail findings in children can be indicative of an underlying systemic disease. Many of these findings are seen in multiple entities and are not specific to one disease. The importance of specifically examining for these nail changes cannot be overstated.
Jane Sanders Bellet
wiley   +1 more source

Spatiotemporal dynamics of brain function network during proprioception rehabilitation after anterior cruciate ligament reconstruction: A randomized trial

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
The improvement of proprioceptive function after ACLR is related to the optimization of spatiotemporal dynamics of SM, CC, DM, CB and VI functional networks. Rehabilitation optimization can incorporate visual–cognitive dual‐task exercises. Abstract Purpose In this study, we aimed to examine the dynamic functional network connectivity (dFNC) patterns ...
Xiaoyun Zhuang, Chunmei Sui, Xuesong Han, Xiaoying Liu, Xiaoyang Wang, Xiumei Zhu, Ming Xu, Yin Qin   +7 more
wiley   +1 more source

Clinical Outcome Assessments for Functional Performance in Spastic Paresis: Systematic Review, Critique, and Recommendations

Movement Disorders, EarlyView.
Abstract Background Spastic paresis, resulting from central nervous system lesions, significantly impairs functional performance. In the framework of the International Classification of Functioning, Disability, and Health, functional performance was defined as functioning at the activity level in relation to the impairment of body functions and ...
Martina Hoskovcova, Marjolaine Baude, Bo Biering‐Sørensen, Ota Gal, Mary P Galea, Jean‐Michel Gracies, Carmen Rodriguez‐Blazquez, Theodore Wein, Michelle Hyczy de Siqueira Tosin, Álvaro Sánchez‐Ferro, Tiago A Mestre, Matej Skorvanek, Robert Jech, The members of the MDS Clinical Outcome Assessments Scientific Evaluation Committee and MDS Spasticity Study Group   +13 more
wiley   +1 more source