Results 21 to 30 of about 147 (139)
Advanced Science, EarlyView.Lithium‐epigallocatechin gallate nanoparticles (Li‐EGCG NPs) are co‐transplanted with embryonic stem cell‐derived retinal ganglion cells (ESC‐RGCs) to enhance cell survival and therapeutic efficacy in an acute pathological glaucomatous injury model. This synergistic approach protects RGC cells, preserves retinal structure and improves visual function ...
Moxin Chen +14 more
wiley +1 more source
Ergative case, aspect and person splits: Two case studies [PDF]
Acta Linguistica Hungarica, 2015 Ergativity splits between perfect and imperfective/progressive predicates are observed in languages with a specialized ergative case (Punjabi) and without it (Kurdish). Perfect predicates correspond to a VP projection; external arguments are introduced by means of an oblique case, namely an elementary part–whole predicate saying that the event is ...
MANZINI, MARIA RITA +2 more
openaire +3 more sources
Advanced Science, EarlyView.GNL3 is a novel AR coregulator with dual coactivator and corepressor functions in prostate cancer (PCa). Our study uncovers a previously unrecognized mechanism by which the AR transcriptional complex integrates oncogenic signaling and immune suppression.
Cuiting Zhang +12 more
wiley +1 more source
Advanced Science, EarlyView.Ng et al. show that the BCR::ABL1 kinase that drives the lymphoid leukemia Ph+B‐ALL modulates enhancer function by coopting signaling‐inducible transcription factors such as MYC, STAT5, and ETV5. BCR::ABL1 thereby promotes the transcriptional program driving and defining this leukemia and renders Ph+B‐ALL cells hypersensitive to enhancer‐inhibiting ...
Han Leng Ng +19 more
wiley +1 more source
Antifunctionality in Shawi split ergativity, a processing analysis
Revista Brasileira de Linguística Antropológica, 2023 In this article, as a follow-up of Rojas-Berscia and Bourdeau (2017), we study morphological ergativity in Shawi (Kawapanan) using a dedicated experimental design. Shawi displays ergative-marking in an opposite direction from Silverstein’s Nominal Hierarchy (NH) (Silverstein 1976).
Rojas-Berscia, Luis Miguel +3 more
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Cortical Somatostatin Neurons Regulate Seizure Susceptibility via MINAR1/Gαs–cAMP Signaling
Advanced Science, EarlyView.Our study identifies MINAR1 as a novel regulator of cortical interneuron excitability and seizure susceptibility. MINAR1 is preferentially expressed in SST+ interneurons. Genetic ablation of MINAR1 leads to seizure hypersensitivity, reduced SST+ neuron excitability, and impaired Gαs–cAMP signaling, disrupting the E/I balance.
Wei‐Tang Liu +20 more
wiley +1 more source
Advanced Science, EarlyView.Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong +24 more
wiley +1 more source
Some notes on split ergativity in Hittite [PDF]
Linguistic Frontiers, 2019 Abstract The Hittite grammar is characterized by a morphosyntactic split that affects the behaviour of the inflectional classes of Noun phrases (DPs). While a singular neuter transitive subject is marked by /-anza/suffix, commons DPs end with an /-š/mark.
openaire +1 more source
Peptide‐Incorporated Biomaterials Promote Regeneration of Peripheral Nerve Injuries
Advanced Science, EarlyView.Peptide‐incorporated biomaterials provide precise, tunable biological cues that mimic functional protein domains to regulate behaviors of neurons, Schwann cells, immune cells, and endothelial cells, thereby enhancing axon elongation, Schwann cell support, inflammatory microenvironment modulation, and vascularization, offering a promising alternative to
Zhiwei Zhao +5 more
wiley +1 more source
Quantifying the Impact of Relativistic Precession on Tidal Disruption Event Light Curves
Astronomische Nachrichten, EarlyView.ABSTRACT The tidal field of a black hole can turn a star into a gas stream whose orbit can precess, especially if the a black hole is rapidly spinning. In this work, we investigate the impact of precession on the light curves of tidal disruption events (TDE).
Diego Calderón +4 more
wiley +1 more source