Results 61 to 70 of about 147 (139)

Cardiac remodelling in type 2 diabetes: Pathophysiological mechanisms and opportunities for multiscale computational modelling and simulation

The Journal of Physiology, EarlyView.
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand, Jakub Tomek, Blanca Rodriguez   +2 more
wiley   +1 more source

Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes

The Journal of Physiology, EarlyView.
Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière, Thomas Boulin, Maëlle Jospin, Alexandre Janin, Gilles Millat, Philippe Chevalier, Olga Andrini   +6 more
wiley   +1 more source

Kinship‐based deference among Jaru siblings: A collaborative, adaptive, and multimodal accomplishment

Journal of Linguistic Anthropology, Volume 36, Issue 1, May 2026.
Abstract In the Jaru community of northern Western Australia, certain in‐laws and relatives are categorized as being in a highly respectful relationship in which they are expected to pay deference to one another. This conversation‐analytic study closely examines the deferential practices that are used among three Jaru siblings in an ordinary multi ...
Josua Dahmen
wiley   +1 more source

Multicentre Evaluation of an AI‐Assisted Urine Test for Clinically Significant Prostate Cancer in Men Undergoing Initial Biopsy

Journal of Extracellular Vesicles, Volume 15, Issue 4, April 2026.
ABSTRACT The Extracellular Vesicles Gene‐based Prostate Score (EGPS), powered by DeepSeek, is an artificial intelligence (AI) diagnostic tool that enhances the detection of clinically significant prostate cancer (csPCa) using urinary EV‐derived gene expression, without requiring digital rectal examination (DRE).
Shaoqin Jiang, Chunguang Yang, Zhangcheng Huang, Zebang Guo, Feiting Lu, Xinwen Nian, Zhenlin Chen, Pengwei Luo, Jiawei Jiang, Xu Gao, Mengqiang Li, Fei Liu   +11 more
wiley   +1 more source

The Homeobox Genes: Classification, Regulation, Biological Functions, and Diseases

MedComm, Volume 7, Issue 4, April 2026.
Overview of the homeobox gene superfamily and its pathophysiological roles. The homeobox superfamily comprises several major classes, including ANTP, PRD, TALE, LIM, POU, and others. Among these, the HOX clusters (A–D) play critical roles in embryonic development specifically in conferring cellular identity, regulating morphogenesis, and guiding axial ...
Maedeh Dadzadi, Shahin Ramazi, Mona Darvazi, Sepideh Yoosefi, Melika Abbasi, Shirin Farsad   +5 more
wiley   +1 more source

Split ergativity in Nêlêmwa

, 1997
Nêlêmwa (New Caledonia) is a split ergative language. Pronouns are accusative, while nominal arguments are marked as ergative-absolutive. The two ergative markers signal the distinction between animate and inanimate agents. With active intransitive verbs (motion, position, affect, perception, cognition, discourse, Aktionsart), there is a choice of ...
openaire   +2 more sources

Liquid–Liquid Phase Separation in Viral Infection and Immunology

MedComm, Volume 7, Issue 4, April 2026.
LLPS organizes viral replication and antiviral immunity. Viruses hijack LLPS to form replication factories and evade immune sensors, while hosts assemble LLPS‐driven signaling hubs (e.g., MAVS, RIG‐I, and SGs) to amplify interferon responses. Targeting these condensate interfaces offers novel therapeutic strategies against infectious diseases ...
Jiuzhi Xu, Lan Bai, Bin Wang, Hai Song, Long Zhang, Fangfang Zhou   +5 more
wiley   +1 more source

Dispersal and delimitation: Phylogenomics of Connaraceae prompts revised generic delimitation in Cnestideae and reveals global biogeographic patterns

TAXON, Volume 75, Issue 2, April 2026.
Abstract The tempo and mode of assembly of the world's most diverse, tropical floras remain poorly known. Evolutionary relationships within pantropical plant clades such as Connaraceae (Oxalidales, ca. 220 species) offer an opportunity to address this issue.
Serafin J.R. Streiff, Jurriaan M. de Vos
wiley   +1 more source

Strengthening Potentials of Lithium‐Doped Soda–Lime–Silicate Glasses Through Surface Crystallization of Quartz‐ss

International Journal of Applied Glass Science, Volume 17, Issue 2, April 2026.
ABSTRACT The formation of a crystallized surface layer, having a lower coefficient of thermal expansion (CTE) than the parent glass, can be exploited to place the glass surface under compression during cooling from crystallization temperature and hence improve mechanical properties.
Fabian Stoelzel, Thorsten Gerdes
wiley   +1 more source

New Insights Into Lakota Syntax: The Encoding of Arguments and the Number of Verbal Affixes

Studia Linguistica, Volume 80, Issue 1, April 2026.
ABSTRACT This paper examines the morphosyntax of transitive constructions in Lakota, with particular emphasis being placed on the encoding of arguments. The analysis of argument marking through verbal affixes in Lakota transitive constructions raises two main questions: the existence or non‐existence of the zero marker for the third person singular and
Avelino Corral Esteban
wiley   +1 more source