Results 201 to 210 of about 5,170,245 (289)

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Efficacy of 1064-nm Picosecond Laser in the Treatment of Lichen Planus Pigmentosus: A Split-Face Randomized Controlled Trial. [PDF]

J Cosmet Dermatol
Rutnin S, Smitthisakda S, Wittayabusarakam N, Yongpisarn T, Sakpuwadol N, Thadanipon K.   +5 more
europepmc   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Reconstructive, functional and psychological outcomes in invasive group A streptococcal soft tissue infections: a 10-year retrospective cohort study 2013-2022. [PDF]

BMC Infect Dis
Vyas R, Nagarajan M, Hamnett K.
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Conjoint tendon split approach for humeral head extraction in acute anterior-to-inferior glenoid rim-incarceration fracture-dislocation and chronic locked anterior dislocation. [PDF]

JSES Rev Rep Tech
Hirosawa N, Kuniyoshi K, Kajiwara D, Ochiai N, Sugaya H.   +4 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

A retrospective review of sagittal split ramus osteotomy: Incidence and risk factors for neurosensory disturbance of the inferior alveolar nerve. [PDF]

PLoS One
Watanabe T, Inoue S, Okada R, Uozumi R, Sasaki M, Kawamura T, Fukuhara S, Hirota M.   +7 more
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Maturation of Elasticity, Pliability and Colour of Thin Split-Thickness Skin Grafts on Deep Dermal and Muscular Wound Bed Within the Course of 1 Year. [PDF]

Int Wound J
Illg C, Gaag A, Rachunek-Medved K, Thiel JT, Daigeler A, Krauss S.   +5 more
europepmc   +1 more source