Results 161 to 170 of about 221,778 (302)

Tailor-made split-plot designs for mixture and process variables

open access: yes, 2007
The design of efficient small experiments involving mixture variables and process variables is a difficult problem. An additional complication is that such experiments are often conducted using split-plot designs and therefore lead to correlated ...
Goos, Peter, Donev, Alex
core  

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Incomplete split-plot designs generated by some resolvable balanced designs

open access: yes
In the paper, we propose new incomplete split-plot designs. The designs proposed are obtained by some modified Kronecker product of two components designs, one for whole-plot treatments and second for subplot treatments. The new designs are characterized
Jimbo, Masakazu   +4 more
core  

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

Comparing fractional CO₂ laser and needling-based modalities in facial acne scar treatment: a comprehensive systematic review and meta-analysis. [PDF]

open access: yesLasers Med Sci
Batool A   +13 more
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Split-plot experiments with factor-dependent whole-plot sizes

open access: yes
In industrial split-plot experiments, the number of runs within each whole plot is usually determined independently from the factor settings. As a matter of fact, it is often equal to the number of runs that can be done within a given period of time or ...
JONES, Bradley   +2 more
core  

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