Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
The effectiveness of lower-level laser therapy on the treatment of minor recurrent aphthous ulcers: a systematic review and meta-analysis. [PDF]
Ma Y, Yang M, Sun J, Qu X, Qu Z, Qu W.
europepmc +1 more source
Trellis plots as visual aids for analyzing split plot experiments
M. Kulahci, Anil Menon
semanticscholar +1 more source
Relative Efficiency of split plot design [PDF]
DHAMU A.P, A SHANMUGASUBRAMANIAN
openalex +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Clinical Performance and Survival of Bulk-Fill Resin Composites Compared to Conventional Resin Composites in Posterior Permanent Teeth: A Systematic Review and Meta-analysis. [PDF]
Zailai A +14 more
europepmc +1 more source
Scatter plots of and split ratios in selected chemostat cultures
Schuetz Robert, Kuepfer Lars, Sauer Uwe
openalex +1 more source
Factor screening experiments using fractional factorial split plot designs and regression analysis in developing a top-down nanomanufacturing system for recycling of welding rod residuals [PDF]
Michael W. Hester, John M. Usher
openalex +1 more source
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source

