The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
The D-optimal design of blocked and split-plot experiments with mixture components. [PDF]
So far, the optimal design of blocked and split-plot experiments involving mixture components has received scant attention. In this paper, an easy method to construct efficient blocked mixture experiments in the presence of fixed and/or random blocks is ...
Goos, Peter, Donev, AN
core
Duplicity as the Story of a Character’s Split Personality: From F. Dostoyevsky’s The Double to B. Anderson’s The Machinist [PDF]
The article examines screen interpretations of Fyodor Dostoyevsky’s novella The Double. The subject of analysis is the plot about doppelgängers as a story the protagonist’s personality split.
Otradnaya Evgeniya S.
doaj +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
EFFECTS OF ROW SPACING AND SEEDING RATES ON SOME AGRONOMICAL TRAITS OF SPRING CANOLA (BRASSICA NAPUS L.) CULTIVARS [PDF]
The objective of the study was to evaluate the effects of row spacing and seeding rates on agronomical traits of three spring canola (Brassica napus L.) cultivars in Iran during 2003-2004. Traits evaluated were plant height, number of seeds pod-1, number
Yazdifar SHAHIN, Ramea VALIOLLAH
doaj
Variations in response pattern of maize (Zea mays)grown at plant populations, defoliated at post-anthesis in the rainforest were tested. Two field trials were conducted at Abeokuta, (Longitude 3025’E, Latitude 7015’N; 144 m a.s.l) and Ibadan (3056’E ...
Olalekan Suleiman SAKARIYAWO +3 more
doaj +1 more source
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
The Waterlogging Tolerance of Wheat Varieties in Western of Turkey
This research was conducted to determine the wheat varieties against waterlogging which was clearly increased in recent years. For this purpose, this study was performed at Field Crops and Soil Science Department of Agricultural Faculty of Adnan Menderes
Ilkay Yavas, Aydin Unay, Mehmet Aydin
doaj +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source

