Results 101 to 110 of about 43,486 (293)

Working memory features are embedded in hippocampal place fields

open access: yesCell Reports
Summary: Hippocampal principal neurons display both spatial tuning properties and memory features. Whether this distinction corresponds to separate neuron types or a context-dependent continuum has been debated.
Viktor Varga   +5 more
doaj   +1 more source

splitter n

open access: yes, 1988
splitter nThe colorful terms cut-throater, header and splitter were the names applied to people who carried out the first three steps in the processing of fish.PRINTED ITEM DNE SupG. M. Story MAY 20 1988WK [Add to DNE splitter n 1, to 1969 quot]Used

core  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Compact and Ultra-Broadband 3 dB Power Splitter Based on Segmented Adiabatic Tapered Rib Waveguides

open access: yesPhotonics
Optical 3 dB power splitters are fundamental building blocks for advanced silicon photonic integrated circuits, with applications ranging from high-speed modulators to optical phased arrays and programmable photonic processors.
Zhen Li, Xin Fu, Lin Yang
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

splitter

open access: yes, 1968
splitter nThe names of Header, Cutt Throat, Carver, Splitter and Salter are the appellations given to the Fishermen who perform the various offices in the stages or in the Rooms.PRINTED ITEM DNE-cit22 July 68 W.J.KIRWINUsed I and SupUsed I and ...

core  

Photonic crystal interfaces: a design-driven approach [PDF]

open access: yes, 2006
Photonic Crystal structures have been heralded as a disruptive technology for the miniaturization of opto-electronic devices, offering as they do the possibility of guiding and manipulating light in sub-micron scale waveguides.
Ayre, Melanie
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

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