Emerging cGAS-STING Agonist-Based Nanotherapeutics: Mechanistic Insights and Applications in Cancer Combination Therapy. [PDF]
This review summarizes recent advances in cGAS‐STING agonist‐based nanotherapeutics for cancer combination therapy. It explores nanoparticle‐mediated delivery strategies, underlying molecular mechanisms, and combinatorial applications with chemotherapy, radiotherapy, targeted therapy, phototherapy, sonodynamic therapy, and immunotherapy.
Wang Z, Wang Y, He Z, Liu C.
europepmc +2 more sources
Assessment of SPND Signal in IFMIF-DONES using a Monte Carlo Modelling [PDF]
IFMIF-DONES (International Fusion Materials Irradiation Facility-DEMO Oriented Neutron Source) is a key facility for the study and analysis of the materials properties exposed to irradiation conditions characterised by a high neutron flux with high energies up to 55 MeV. These irradiation conditions are expected by the future DEMOnstration fusion power
Álvarez, Irene +9 more
openaire +3 more sources
Response of the SPND measurement system to temperature during the Three Mile Island Unit 2 accident. [Self-Powered Neutron Detector] [PDF]
The Self-Powered Neutron Detector (SPND) Measuring System is evaluated to determine its ability to indicate temperatures of the fuel rods in the TMI-2 reactor core during the accident. It is concluded for the following reasons that the SPND Measuring System did not provide fuel rod temperatures during the accident: the heat transfer characteristics ...
Wilde, N., Morrison, J.L. Jr.
openaire +3 more sources
Study of neutron sensitivity for vanadium self-powered neutron detector in nuclear reactors
Vanadium self-powered neutron detectors (SPNDs) are widely used as in-core unmovable detectors in nuclear power plants to continuously carry out data monitoring of neutron flux and nuclear power.
Xiong Wu +4 more
doaj +2 more sources
Compton-emissive hafnium detector of neutrons for in-core monitoring
The work is devoted to substantiating the use of metallic hafnium as the emitter of the Compton (prompt-response) in-core detector of thermal and resonant neutrons. The main trends in the development of nuclear power engineering, which raise the interest
A. L. Ulybkin +5 more
doaj +2 more sources
Model of formation of in-core neutron detector signal
Fuel rods linear power rate is one of the most important indicators of safety and operating reliability of VVER fuel. The article describes the evolution of implementation of in-core monitoring system (ICMS) power distribution control function for VVER ...
V. I. Borysenko +2 more
doaj +1 more source
BackgroundThe vanadium self-powered neutron detector (SPND) generates significant gamma noise current in the mixed radiation field of a nuclear reactor, which adversely affects the accuracy of neutron flux measurements and online monitoring of reactor ...
ZHOU Yao +6 more
doaj +2 more sources
Calculation of the signal current of self-powered neutron detectors in a nuclear reactor
BackgroundSelf-powered neutron detectors (SPNDs) are critical devices in the monitoring and protection systems of nuclear reactors, and their signal current directly reflects the value and distribution of the core power. Insulators play an essential role
WU Xiong +3 more
doaj +2 more sources
MONACO v2: Multipurpose and Integrated Data Acquisition System for On-line Neutron and Gamma Measurements [PDF]
The CEA MONACO v2 a multichannel acquisition system dedicated to neutron and gamma measurements. It is unique as it integrates all the following features in one module: automatic generation of saturation curves, automatic generation of pulse ...
Barbot L. +6 more
doaj +1 more source
Design of High-Gain Signal Amplifier Circuit for Prompt-Response Self-Powered Neutron Detector [PDF]
Self-Powered neutron detectors (SPND) detect current generated from interaction of neutron flux with emitter materials. They are inside a reactor in NPP (Nuclear Power Plant), and currently used to monitor the output and control the operation.
Heejune Park +2 more
doaj +1 more source

