A New Type of Spacer Oligonucleotide Typing for Mycobacterium Tuberculosis Complex and Clinical Evaluation [PDF]
结核病是当今世界范围内对人类健康最具威胁的传染性疾病之一,具有潜伏感染的特点,因此追踪传染源和查证传播途径是长期困扰结核病流行病学研究的一个问题,也是分子流行病学要解决的首要问题。基因分型技术是分子流行病学研究的一个有力工具,在研究结核病传播规律方面有着不可替代的优势。一个理想的基因分型技术应当具备简便、快速、结果可在不同实验室间进行比较等特点。本论文基于探针熔解曲线分析技术,建立新型的快速结核分枝杆菌分型体系,并评价其临床应用。论文内容如下: 第一章为绪论,首先概述了结核病目前的流行情况 ...
曾小红
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BACKGROUND: Treatment options for drug-resistant tuberculosis (DR-TB) are limited. Linezolid has been successfully used to treat DR-TB in adults, but there are few case reports of its use in children for TB.
Hallbauer, UM+4 more
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Predominance of Ancestral Lineages of Mycobacterium tuberculosis in India
Although India has the highest prevalence of tuberculosis (TB) worldwide, the genetic diversity of Mycobacterium tuberculosis in India is largely unknown.
M. Cristina Gutierrez+9 more
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Molecular genotyping of mycobacterium tuberculosis associated with extrapulmonary tuberculosis [PDF]
Recent advances in molecular typing provide a robust tool to analyse the heterogeneity of Mycobacterium tuberculosis strains as well as their transmission patterns.
Ayub, Nur Izzah Farakhin
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Spoligotyping Followed by Double-Repetitive-Element PCR as Rapid Alternative to IS 6110 Fingerprinting for Epidemiological Studies of Tuberculosis [PDF]
Christophe Sola+5 more
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Study of Restriction Fragment Length Polymorphism Analysis and Spoligotyping for Epidemiological Investigation of Mycobacterium bovis Infection [PDF]
Eamon Costello+7 more
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Characterization of Mycobacterium tuberculosis Isolates from Patients in Houston, Texas, by Spoligotyping [PDF]
Hanna Soini+5 more
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Türkiye’de Sığırlardan İzole Edilen M. tuberculosis Suşlarının Spoligotiplendirmesi
Although it is generally accepted that M.bovis leads to tuberculosis in cattle, there are statements given from the different regions of the world, referring to the fact that M. tuberculosis, which is known as the human tuberculosis agent, causes tuberculosis in cattle as well. The material of the study consisted of 13 M.
Tuzcu, Nevin+5 more
openaire +6 more sources
Molecular typing of mycobacterium tuberculosis by using nine novel variable-number tandem repeats across the Beijing family and low-copy-number IS6110 isolates [PDF]
Molecular epidemiological tools for genotyping clinical isolates of Mycobacterium tuberculosis have been developed and used to help track and contain transmission of tuberculosis.
Cox, Rebecca A.+6 more
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Spoligotyping analysis of Mycobacterium tuberculosis in Khyber Pakhtunkhwa area, Pakistan
Sajid Ali,1 Muhammad Tahir Khan,2 Khan Anwar Sheed,3 Muhammad Mumtaz Khan,4 Fariha Hasan11Department of Microbiology, Quaid-i-Azam University, Islamabad, Pakistan; 2Department of Bioinformatics and Biosciences, Capital University of Science and ...
Ali S+4 more
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