Clinical Impact of HLA‐B27 on Juvenile Idiopathic Arthritis: Eighteen Years of Follow‐up in the Population‐Based Nordic Juvenile Idiopathic Arthritis Cohort [PDF]
Objective We have previously shown that HLA‐B27 was negatively associated with remission status eight years after the onset of juvenile idiopathic arthritis (JIA).
Maria Ekelund +12 more
doaj +3 more sources
Tumor necrosis factor inhibitors are associated with reduced complement activation in spondylarthropathies: An observational study. [PDF]
BackgroundThe complement system is involved in pathogenesis of cardiovascular disease, and might play a role in accelerated atherogenesis in spondylarthropathies (SpA).
Ingrid Hokstad +8 more
doaj +4 more sources
Impact of disease outcomes on the Assessment of SpondyloArthritis International Society Health Index (ASAS HI): a Bayesian network analysis of the DESIR cohort [PDF]
Objective The objective of this study is to build a structural model visualising and quantifying the interrelationships of different disease outcomes with the Assessment of SpondyloArthritis International Society Health Index (ASAS HI) in patients with ...
Sofia Ramiro +7 more
doaj +2 more sources
Humoral and Cellular Immunogenicity and Safety of Five Different SARS-CoV-2 Vaccines in Patients With Autoimmune Rheumatic and Musculoskeletal Diseases in Remission or With Low Disease Activity and in Healthy Controls: A Single Center Study [PDF]
BackgroundVaccine-induced immunity is essential for controlling the COVID-19 pandemic. Data on humoral and cellular immunogenicity and safety of different SARS-CoV-2 vaccines in patients with autoimmune rheumatic and musculoskeletal diseases (RMDs) are ...
Gábor J. Szebeni +16 more
doaj +2 more sources
Persistence of biological agents over an eight-year period in rheumatoid arthritis and spondyloarthritis patients [PDF]
Objective: To calculate the persistence, over a period of eight years, the retention rate of first and second-line of treatment with biological agents in patients with rheumatoid arthritis, spondyloarthritis and psoriatic arthritis and to compare ...
María Ángeles González-Fernández +5 more
doaj +5 more sources
Successful Treatment of Post-SARS-CoV-2 Infection Reactive Arthritis With Secukinumab: A Case Report and Literature Review. [PDF]
ABSTRACT This case describes a rare occurrence of post‐SARS‐CoV‐2 infection reactive arthritis with psoriasiform lesions. The patient failed to respond to conventional therapies but responded well to secukinumab, underscoring that it may be a valuable treatment for refractory post‐SARS‐CoV‐2 infection reactive arthritis when conventional therapies fail.
Zhao Q +11 more
europepmc +2 more sources
Imaging Outcomes for Axial Spondyloarthritis and Sensitivity to Change: A Five-Year Analysis of the DESIR Cohort. [PDF]
Objective To compare the sensitivity to change of different imaging scoring methods in patients with early axial spondyloarthritis (SpA). Methods Patients from the Devenir des Spondylarthropathies Indifferérenciées Récentes (DESIR) cohort fulfilling the Assessment of SpondyloArthritis international Society criteria for axial SpA were included ...
Sepriano A +8 more
europepmc +2 more sources
Inflammation of the Sacroiliac Joints and Spine and Structural Changes on Magnetic Resonance Imaging in Axial Spondyloarthritis: Five-Year Data From the DESIR Cohort. [PDF]
Objective To test the impact of inflammation on structural changes occurring in the sacroiliac (SI) joints and the spine detected on magnetic resonance imaging (MRI). Methods Patients with early axial spondyloarthritis (SpA) from the Devenir des Spondylarthropathies Indifferérenciées Récentes (DESIR) cohort were included.
Sepriano A +7 more
europepmc +2 more sources
Association between sarcopenia and physical activity in individuals with spondyloarthritis [PDF]
Objective: To assess the association between sarcopenia and physical activity in individuals with spondyloarthritis (SpA). Methods: Physical functional performance of individuals with SpA (SpA group [SG]: n=29, 10 males, mean age=50.6±10.2 years) and a ...
Bruna Oliveira Corrêa do Amaral +4 more
doaj +2 more sources
Different disease activity trajectories in early axial spondyloarthritis lead to significantly different long-term outcomes: a trajectory-based analysis of the DESIR cohort over 10 years [PDF]
Introduction The study aimed to identify and describe disease activity trajectories over 10 years in patients with recent-onset axial spondyloarthritis (axSpA) and determine their impact on long-term outcomes.Methods This prospective, multicentre study ...
Maxime Dougados +5 more
doaj +2 more sources

