Clinical Impact of HLA‐B27 on Juvenile Idiopathic Arthritis: Eighteen Years of Follow‐up in the Population‐Based Nordic Juvenile Idiopathic Arthritis Cohort [PDF]
Objective We have previously shown that HLA‐B27 was negatively associated with remission status eight years after the onset of juvenile idiopathic arthritis (JIA).
Maria Ekelund +12 more
doaj +3 more sources
Tumor necrosis factor inhibitors are associated with reduced complement activation in spondylarthropathies: An observational study. [PDF]
BackgroundThe complement system is involved in pathogenesis of cardiovascular disease, and might play a role in accelerated atherogenesis in spondylarthropathies (SpA).
Ingrid Hokstad +8 more
doaj +4 more sources
Impact of disease outcomes on the Assessment of SpondyloArthritis International Society Health Index (ASAS HI): a Bayesian network analysis of the DESIR cohort [PDF]
Objective The objective of this study is to build a structural model visualising and quantifying the interrelationships of different disease outcomes with the Assessment of SpondyloArthritis International Society Health Index (ASAS HI) in patients with ...
Sofia Ramiro +7 more
doaj +2 more sources
Humoral and Cellular Immunogenicity and Safety of Five Different SARS-CoV-2 Vaccines in Patients With Autoimmune Rheumatic and Musculoskeletal Diseases in Remission or With Low Disease Activity and in Healthy Controls: A Single Center Study [PDF]
BackgroundVaccine-induced immunity is essential for controlling the COVID-19 pandemic. Data on humoral and cellular immunogenicity and safety of different SARS-CoV-2 vaccines in patients with autoimmune rheumatic and musculoskeletal diseases (RMDs) are ...
Gábor J. Szebeni +16 more
doaj +2 more sources
Persistence of biological agents over an eight-year period in rheumatoid arthritis and spondyloarthritis patients [PDF]
Objective: To calculate the persistence, over a period of eight years, the retention rate of first and second-line of treatment with biological agents in patients with rheumatoid arthritis, spondyloarthritis and psoriatic arthritis and to compare ...
María Ángeles González-Fernández +5 more
doaj +5 more sources
Association between sarcopenia and physical activity in individuals with spondyloarthritis [PDF]
Objective: To assess the association between sarcopenia and physical activity in individuals with spondyloarthritis (SpA). Methods: Physical functional performance of individuals with SpA (SpA group [SG]: n=29, 10 males, mean age=50.6±10.2 years) and a ...
Bruna Oliveira Corrêa do Amaral +4 more
doaj +2 more sources
Different disease activity trajectories in early axial spondyloarthritis lead to significantly different long-term outcomes: a trajectory-based analysis of the DESIR cohort over 10 years [PDF]
Introduction The study aimed to identify and describe disease activity trajectories over 10 years in patients with recent-onset axial spondyloarthritis (axSpA) and determine their impact on long-term outcomes.Methods This prospective, multicentre study ...
Maxime Dougados +5 more
doaj +2 more sources
Genetic control of experimental spondylarthropathy [PDF]
AbstractObjectiveTo characterize experimentally induced spondylarthropathy (SpA) in arthritis‐susceptible inbred mice and in their F1 and F2 hybrid generations of susceptible and resistant mouse strains.MethodsSpA was induced in susceptible BALB/c and C3H/HeJCr (C3H) strains of mice, and in their F1 and F2 generations derived from intercrosses with ...
Zoltán, Szabó +5 more
openaire +4 more sources
Trends in medications for autoimmune disorders during pregnancy and factors for their discontinuation: a population-based study [PDF]
Objectives The medications used for autoimmune diseases have significantly evolved in recent years, but there is limited knowledge about how treatment practices changed during pregnancy.
Sabine Mainbourg +4 more
doaj +2 more sources
The spondyloarthropathies are a group of related conditions which have in common genetic factors, clinical features and a specific pathological target: the enthesis.
Sébastien Villotte, Sacha Kacki
doaj +2 more sources

