Original paper Prevalence of HLA-B27 antigen in patients with juvenile idiopathic arthritis [PDF]
Rheumatology, 2015 Introduction: Human leukocyte antigen B27 (HLA-B27) is considered as a risk factor for development of juvenile idiopathic arthritis (JIA). The aim of this study was to analyse the prevalence of HLA-B27 antigen in JIA categories and its influence on ...
Zbigniew Żuber +3 more
doaj +5 more sources
HLA B27 antigen in Middle Eastern and Arab countries: systematic review of the strength of association with axial spondyloarthritis and methodological gaps [PDF]
BMC Musculoskeletal Disorders, 2017 Background Axial spondyloarthritis (AxSpA) is a relatively frequent and debilitating disease, with a prevalence ranging from 0.1 to 2% in the Caucasian population.
Nelly Raymond Ziade
doaj +2 more sources
Autoinflammation and HLA-B27: Beyond Antigen Presentation [PDF]
Ocular Immunology and Inflammation, 2016 HLA-B27 associated disorders comprise a group of inflammatory conditions which have in common an association with the HLA class I molecule, HLA-B27. Given this association, these diseases are classically considered disorders of adaptive immunity. However, mounting data are challenging this assumption and confirming that innate immunity plays a more ...
Cailin H Sibley
exaly +3 more sources
Does HLA-B27 Status Influence Ixekizumab Efficacy in Axial Spondyloarthritis? Results From the COAST-V, COAST-W, and COAST-X Trials [PDF]
Rheumatology and TherapyIntroduction The human leukocyte antigen (HLA)-B27 is associated with axial spondyloarthritis (axSpA) and is a predictor of response to tumor necrosis factor inhibitors. However, limited data are available on HLA-B27 and interleukin-17 inhibitors.
John D. Reveille +11 more
doaj +2 more sources
Bilateral Avascular Necrosis of the Femoral Heads in Ankylosing Spondylitis Requiring Staged Total Hip Arthroplasty: A Case Report of Diagnostic and Therapeutic Challenges. [PDF]
Clin Case RepABSTRACT Ankylosing spondylitis (AS) is a chronic immune‐mediated inflammatory arthropathy primarily affecting the axial skeleton but may involve peripheral joints, particularly the hips. Avascular necrosis (AVN) of the femoral head represents a severe, underrecognized complication whose pathogenesis in AS is multifactorial—encompassing disease ...
Shah SS +5 more
europepmc +2 more sources
Mydriasis as a Secondary Effect in Patients With HLA‐B27–Associated Uveitis
Medicine AdvancesAcute anterior uveitis (AAU) is the most common form of uveitis, and approximately 90% of AAU cases are associated with human leukocyte antigen (HLA)‐B27.
Saim Mahmood Khan +6 more
doaj +2 more sources
HLA-B27-associated gut microbiota and amino acid perturbations promote ankylosing spondylitis through M1 macrophage activation [PDF]
Gut MicrobesAnkylosing spondylitis (AS) is strongly associated with the human leukocyte antigen B27 (HLA-B27), yet how this genetic risk factor interacts with the gut microbiome remains unclear.
Tianwen Huang +9 more
doaj +2 more sources
Hitit Medical JournalObjective: The aim of this study was to research the frequency of Human Leukocyte Antigen (HLA)-B27 antigen positivity and relationship between HLA-B27 positivity and other autoantibodies and between HLA-B27 positivity and ...
Gülseren Demir Karakılıç +2 more
doaj +3 more sources
Association of HLA-B27 antigen with clinical and laboratory parameters in patients with juvenile idiopathic arthritis [PDF]
Medicinski Glasnik, 2023 Aim To analyse the association of human leukocyte antigen B27 with clinical and laboratory parameters in patients with juvenile idiopathic arthritis (JIA) at the disease onset. Methods A retrospective review of medical records of 25 HLAB27 positive and
Adisa Čengić +5 more
doaj +1 more source
HLA-B27 (antigen) in retroperitoneal fibrosis in a family
Archives of Medical Science, 2007 Idiopathic retroperitoneal fibrosis is a rare disease of undetermined aetiology. It is important to distinguish this entity from retroperitoneal fibrosis secondary to malignancy or specific inflammatory disease.
Mohammad Yazdani, Afshin Shadmehr
doaj +1 more source