Results 21 to 30 of about 499,322 (218)

The HLA-E Gene encodes two differentially regulated Transcripts and a Cell Surface Protein [PDF]

open access: yes, 1992
An HLA-E-specific oligonucleotide probe was used to study the expressioonf HLA-E. This probed etects two HLA-E transcripts, 1.8 and 2.7 kb in size, which are present in varying ratios in allt issues and cell lines investigated.
Honka, Thomas   +4 more
core   +1 more source

Clinical Features of Acute Anterior Uveitis with Complicated Course in a Slovenian Patient Population

open access: yesJournal of Ophthalmology, 2020
Purpose. To report on patients who needed hospitalization due to acute anterior uveitis (AAU) and within this group to compare clinical features and outcomes of treatment of HLA-B27+ and HLA-B27− AAU in the population of Slovenian patients.
Katarina Vergot   +3 more
doaj   +1 more source

Clustered mutations in HIV-1 gag are consistently required for escape from HLA-B27-restricted cytotoxic T lymphocyte responses [PDF]

open access: yes, 2000
The immune response to HIV-1 in patients who carry human histocompatibility leukocyte antigen (HLA)-B27 is characterized by an immunodominant response to an epitope in p24 gag (amino acids 263-272, KR WIILGLNK).
Anthony D. Kelleher   +38 more
core   +1 more source

Treatment Responses in Patients With Psoriatic Arthritis Axial Disease According to Human Leukocyte Antigen‐B27 Status: An Analysis From the CorEvitas Psoriatic Arthritis/Spondyloarthritis Registry

open access: yesACR Open Rheumatology, 2022
Objective Axial disease is common and burdensome in patients with psoriatic arthritis (PsA). Human leukocyte antigen‐B27 (HLA‐B27) is a risk factor for axial PsA; treatment response by HLA‐B27 status is inadequately characterized.
Philip J. Mease   +7 more
doaj   +1 more source

Impaired Intracellular Transport and Cell Surface Expression of Nonpolymorphic HLA-E [PDF]

open access: yes, 1992
The assembly of the classical, polymorphic major histocompatibility complex class I molecules in the endoplasmic reticulum requires the presence of peptide ligands and ~2-microglobulin (~2m). Formation of this trimolecular complex is a prerequisite for e~
Kellermann, Josef   +7 more
core   +1 more source

Human Leukocyte Antigen B27‐Negative Axial Spondyloarthritis: What Do We Know?

open access: yesACR Open Rheumatology, 2023
Axial spondyloarthritis (axSpA) is a chronic, immune‐mediated disease characterized by inflammatory axial skeleton involvement and extra‐musculoskeletal manifestations.
Atul Deodhar, Tejpal Gill, Marina Magrey
doaj   +1 more source

Lack of hybridization between Yersinia enterocolitica and HLA-B27 DNA [PDF]

open access: yes, 1988
Inhaltverz.
Viitanen, A. M.   +3 more
core   +1 more source

Inflammatory bowel disease-specific autoantibodies in HLA-B27-associated spondyloarthropathies: Increased prevalence of ASCA and pANCA [PDF]

open access: yes, 2004
Aims: An association between inflammatory bowel disease (IBD) and spondyloarthropathies (SpA) has repeatedly been reported. The aim of the present study was to investigate whether serologic markers of IBD, e. g.
Folwaczny, Christian   +15 more
core   +1 more source

Changes in C-reactive protein, erythrocyte sedimentation rate, human leukocyte antigen-B27, and immunoglobulins A, G, M in patients with ankylosing spondylitis

open access: yesRomanian Journal of Laboratory Medicine, 2023
To explore the changes in C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), human leukocyte antigen-B27 (HLA-B27), and immunoglobulin (Ig) (IgA, IgG, and IgM) in patients suffering from ankylosing spondylitis (AS).
Zhu Lixiu   +5 more
doaj   +1 more source

Genetic and serological heterogeneity of the supertypic HLA-B locus specificities Bw4 and Bw6 [PDF]

open access: yes, 1989
Gene cloning and sequencing of the HLA-B locus split antigens B38 (B16.1) and B39 (B16.2) allowed localization of their subtypic as well as their public specificities HLA-Bw4 or -Bw6 to the c~-helical region of the c~ 1 domain flanked by the amino acid ...
Gekeler, V.   +5 more
core   +1 more source

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