Results 41 to 50 of about 12,527 (175)

Beyond Sequence: Posttranslational Remodeling of Antigens in Autoimmunity

open access: yesImmunological Reviews, Volume 341, Issue 1, August 2026.
ABSTRACT Autoimmune responses are often attributed to failed tolerance to self‐proteins, yet protein expression alone cannot explain why certain antigens dominate disease, why autoreactivity emerges under stress, or why specific HLA alleles shape risk.
Cynthiya Shrestha   +2 more
wiley   +1 more source

PREVALENCE OF HUMAN LEUKOCYTE ANTIGEN (HLA) B27 AMONG PATIENTS OF SPONDYLOARTHROPATHIES REFERRED TO A TERTIARY CARE CENTER

open access: yesPakistan Armed Forces Medical Journal, 2017
Objective: To determine prevalence of HLA-B27 among patients of spondyloarthropathies. Study Design: Cross sectional study. Place and Duration of Study: Department of Immunology, Armed Forces Institute of Pathology Rawalpindi Jan 2015 to Aug 2016 ...
Hamid Nawaz Tipu   +1 more
doaj   +2 more sources

Atypical Case of Takayasu Aortitis Presenting as Embolic Stroke With Concomitant Massive Thoracic Artery Aneurysm

open access: yesClinical Case Reports, Volume 14, Issue 7, July 2026.
Multifocal aortic aneurysmal dilatation as evidenced by CT Angiography chest‐abdomen‐pelvis of the ascending aorta (A), aortic arch (B), and suprarenal abdominal aorta (C), measuring 6.0 × 6.0, 4.5 × 4.5, and 4.1 × 3.7 cm, respectively. ABSTRACT We describe the case of a 44‐year‐old female with a history significant for only hypertension who presented ...
J. Curran Henson   +4 more
wiley   +1 more source

Clinical‐Grade Human Induced Pluripotent Stem Cell‐Derived Neural Precursor Cells Restore Motor Function and Preserve Striatal Integrity in a Quinolinic Acid‐Lesioned Rat Model of Huntington's Disease

open access: yesCell Proliferation, Volume 59, Issue 7, July 2026.
Clinical‐grade HLA‐homozygous iPSC‐derived neural precursor cells restore motor function, rebuild striatal circuitry and reduce neuroinflammation in QA‐lesioned rats. These findings demonstrate robust neuronal replacement and microenvironment modulation, supporting their potential as a regenerative therapy for Huntington's disease.
Hyeonjoong Jeon   +6 more
wiley   +1 more source

Histocompatibility HLA class I in anterior uveitis patients with and without spondyloarthritis

open access: yesСовременная ревматология, 2018
Anterior uveitis (AU) and ankylosing spondylitis (AS) are associated with histocompatibility human leukocyte antigen (HLA)-B27. Previous genetic studies conducted in different populations have also demonstrated other genetic associations, including HLA ...
I. A. Guseva   +2 more
doaj   +1 more source

Machine Learning for TCR Repertoire Epitope Annotation and Pattern Discovery

open access: yesImmunological Reviews, Volume 340, Issue 1, July 2026.
ABSTRACT T cells are central to adaptive immunity, recognizing antigenic peptides, called epitopes, via the T cell receptor (TCR). The immense diversity and cross‐reactivity of the TCR repertoire makes direct interpretation of antigen specificity from repertoire sequencing challenging.
Romi Vandoren   +5 more
wiley   +1 more source

Inflammatory Pseudotumor After Total Hip Arthroplasty‐An Increasingly Recognized Complication

open access: yesOrthopaedic Surgery, Volume 18, Issue 7, Page 1311-1327, July 2026.
This review systematically elucidates the clinical characteristics and management of inflammatory pseudotumor (IP) across different bearing surfaces, addressing a topic of increasing concern and providing a novel perspective. It synthesizes the five primary risk factors associated with IP, offering clinicians critical reference points.
Steve T. L. Pambayi   +8 more
wiley   +1 more source

Isoniazid‐Related Secondary Drug‐Induced Autoimmune Hepatitis in a Patient Diagnosed With Ankylosing Spondylitis and Tuberculous Lymphadenitis: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Autoimmune hepatitis is a type of chronic hepatitis that is usually progressive, has unknown etiology, and can occur at any age. In the present case, drug‐associated autoimmune hepatitis (DIAIH) was discussed, and DIAIH secondary to isoniazid (INH) was found in two case reports in the literature.
Murat AY, Erhan Bozkurt
wiley   +1 more source

Determination of HLA-B27 Subtypes in Iranian Patients with Ankylosing Spondylitis

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2008
The human leukocyte antigen-B27 is one of the class I molecules of the major histocompatibility complex which is strongly associated with ankylosing spondylitis (AS).
Mohamad Hossein Nicknam   +10 more
doaj  

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