Results 51 to 60 of about 499,322 (218)

Preliminary Validation of the Early Sacroiliitis Screening Tool (ESHST) for Identifying Hidradenitis Suppurativa Patients at High Risk of Spondyloarthritis

open access: yesInternational Journal of Dermatology, EarlyView.
Development and preliminary validation of the Early Sacroiliitis Screening Tool (ESHST), a dermatology‐oriented screening questionnaire for identifying hidradenitis suppurativa patients at increased risk of spondyloarthritis. ABSTRACT Background Hidradenitis suppurativa (HS) is increasingly recognized as a systemic inflammatory disease associated with ...
Umut Bakay   +3 more
wiley   +1 more source

The Oxidative Folding and Misfolding of Human Leukocyte Antigen-B27

open access: yes, 2011
The major histocompatibility complex class I molecule human leukocyte antigen (HLA)-B27 is strongly associated with a group of inflammatory arthritic disorders known as the spondyloarthropathies.
Guiliano, D.B.   +4 more
core   +1 more source

Microarray Analysis of Response of Salmonella during Infection of HLA-B27- Transfected Human Macrophage-Like U937 Cells

open access: yesBMC Genomics, 2010
Background Human leukocyte antigen (HLA)-B27 is strongly associated with the development of reactive arthritis (ReA) in humans after salmonellosis. Human monocytic U937 cells transfected with HLA-B27 are less able to eliminate intracellular Salmonella ...
Hinton Jay CD   +4 more
doaj   +1 more source

A PD1‐CD137L Fusion Protein More Potently Enhances Anti‐Tumour Immune Responses Than Targeting PD‐L1 and CD137 Separately

open access: yesImmunology, EarlyView.
A PD1‐CD137L fusion protein converts the immunoinhibitory PD‐L1 to an immunostimulatory signal and is more effective than targeting PD‐L1 and CD137 separately. ABSTRACT Tumour immune evasion frequently involves PD‐L1‐mediated inhibition of T cell activity, limiting the efficacy of PD1/PD‐L1 blockade, particularly in PD‐L1‐low or immunologically ‘cold ...
Runze Xia   +10 more
wiley   +1 more source

Rat models of autoimmune uveitis [PDF]

open access: yes, 2008
Experimental autoimmune uveitis ( EAU) in Lewis rats is a well-established model for human uveitis. During the last years we used this model to demonstrate extraocular induction of uveitis by antigenic mimicry of environmental antigens with retinal ...
Wildner, Gerhild   +2 more
core   +1 more source

A case of reactive arthritis after enteritis in in a 12-year-old boy [PDF]

open access: yesKorean Journal of Pediatrics, 2011
Reactive arthritis comprises a subgroup within infection-associated arthritides in genetically susceptible hosts. Researchers and clinicians recognize two clinical forms of reactive arthritis which occurs after genitourinary tract infection and after ...
Peter Chun   +3 more
doaj   +1 more source

Mimicry of human histocompatibility HLA-B27 antigens by Klebsiella pneumoniae [PDF]

open access: yesInfection and Immunity, 1986
Anti-HLA-B27 monoclonal antibody M2, which was relatively specific for human histocompatibility antigen HLA-B27, was used to test several bacteria, some of which could potentially induce chronic arthritis in HLA-B27-positive individuals. Using the Western blot procedure, we observed positive reactions with 80,000- and 60,000-dalton antigens with one ...
M, Ogasawara, D H, Kono, D T, Yu
openaire   +2 more sources

Prognostic prediction models for psoriatic arthritis in psoriasis: A systematic review

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
This systematic review evaluated prognostic prediction models used to assess the risk of future psoriatic arthritis in psoriasis patients. The included studies reported modest to moderate performance measures, with limited external validation, inadequate reporting and high risk of bias.
Fatimah Khoda   +8 more
wiley   +1 more source

HLA-B27 [PDF]

open access: yes, 2015
Possession of the human leukocyte antigen (HLA) class I molecule B27 is strongly associated with ankylosing spondylitis (AS), but the pathogenic role of HLA-B27 is unknown.
Bowness, Paul, Bowness, P, Paul Bowness
core   +1 more source

PREVALENCE OF HUMAN LEUKOCYTE ANTIGEN (HLA) B27 AMONG PATIENTS OF SPONDYLOARTHROPATHIES REFERRED TO A TERTIARY CARE CENTER

open access: yesPakistan Armed Forces Medical Journal, 2017
Objective: To determine prevalence of HLA-B27 among patients of spondyloarthropathies. Study Design: Cross sectional study. Place and Duration of Study: Department of Immunology, Armed Forces Institute of Pathology Rawalpindi Jan 2015 to Aug 2016 ...
Hamid Nawaz Tipu   +1 more
doaj   +2 more sources

Home - About - Disclaimer - Privacy