Results 51 to 60 of about 12,452 (175)

Determination of HLA-B27 Subtypes in Iranian Patients with Ankylosing Spondylitis

Iranian Journal of Allergy, Asthma and Immunology, 2008
The human leukocyte antigen-B27 is one of the class I molecules of the major histocompatibility complex which is strongly associated with ankylosing spondylitis (AS).
Mohamad Hossein Nicknam, Mahdi Mahmoudi, Ali Akbar Amirzargar, Mazdak Ganjalikhani Hakemi, Farideh Khosravi, Ahmad Reza Jamshidi, Aref Amirkhani, Bita Ansaripour, Zahra Pourpak, Mostafa Moin, Behrooz Nikbin   +10 more
doaj  

Certolizumab Pegol Reduced Anterior Uveitis Flares Compared With Standard Non‐Biologic Treatment: Results From an Overlap Weighting Analysis in High‐Risk Patients With Axial Spondyloarthritis

International Journal of Rheumatic Diseases, Volume 29, Issue 4, April 2026.
ABSTRACT Objective Acute anterior uveitis (AAU) is the most common extra‐musculoskeletal manifestation of axial spondyloarthritis (axSpA). This study compared the effect of the tumor necrosis factor inhibitor (TNFi) certolizumab pegol (CZP) with standard non‐biologic care, on AAU flare rate in patients with axSpA and high risk of recurrent uveitis ...
Nigil Haroon, Zeynep Baskurt, Tina Chim, Robert D. Inman, Thomas Kumke, Rachel Tham, Mindy Kim, Irene van der Horst‐Bruinsma, Lianne S. Gensler   +8 more
wiley   +1 more source

Comprehensive single‐cell profiling of monocytes in HLA‐B27‐positive ankylosing spondylitis with acute anterior uveitis

MedComm
Acute anterior uveitis (AAU) is a common extra‐articular manifestation of ankylosing spondylitis (AS), particularly in patients positive for the human leucocyte antigen (HLA)‐B27 genetic marker.
Huan Li, Xueming Ju, Lixin Zhang, Jing Zhu, Jing Zhang, Jialing Xiao, Ting Wang, Weijia Wu, Liang Wang, Chengzi Gan, Xiangmei Li, Yutong Wei, Siyu Zhu, Yu Zhou, Bolin Deng, Ning Xiao, Bo Gong   +16 more
doaj   +1 more source

Combined detection of HLA-B27, ESR, and CRP as biochemical and immunogenetic markers in the auxiliary diagnosis of ankylosing spondylitis [PDF]

Journal of Medical Biochemistry
Background: Ankylosing spondylitis (AS) is a chronic inflammatory disease in which early diagnosis is often challenging due to atypical clinical manifestations.
Wang Muchuan, Yao Siyuan, Gao Chengao, Wang Yipeng   +3 more
doaj   +1 more source

Decoding the Cellular Heterogeneity and Malignant Progression of Human Penile Squamous Cell Carcinoma by Single‐Cell RNA Sequencing

Advanced Science, Volume 13, Issue 14, 9 March 2026.
Single‐cell transcriptomic and functional analyses identify SEMA3C as a key regulator of tumor progression and tumor microenvironment remodeling in penile squamous cell carcinoma. SEMA3C promotes epithelial–mesenchymal transition, tumor growth, and invasion while shaping an immunosuppressive microenvironment, highlighting its potential as a prognostic ...
Xiheng Hu, Wensheng Shi, Liang Dong, Lingjuan Huang, Xiyuan Zhang, Yiting Feng, Jie Sun, Lanlan Liu, Teng Liu, Jun Fu, Bowen Zhong, Qihao Leng, Xiaohua Wu, Minfeng Chen, Lingfang Li, Yuan Li, Xin Jin, Long Wang, Jian Cao, Xin Li, Mingzhu Yin, Xiang Chen   +21 more
wiley   +1 more source

Human Leukocyte Antigen-B27 and Disease Susceptibility in Vojvodina, Serbia

Balkan Journal of Medical Genetics, 2012
There are numerous studies showing the role of human leukocyte antigens (HLAs) related with susceptibility or resistance to certain diseases.
Vojvodić S., Ademović-Sazdanić D., Busarčević I.   +2 more
doaj   +1 more source

Targeted Delivery of the HLA-B∗27-Binding Peptide into the Endoplasmic Reticulum Suppresses the IL-23/IL-17 Axis of Immune Cells in Spondylarthritis

Mediators of Inflammation, 2017
Ankylosing spondylitis (AS) is highly associated with the expression of human leukocyte antigen-B27 (HLA-B∗27). HLA-B∗27 heavy chain (B27-HC) has an intrinsic propensity to fold slowly, leading to the accumulation of the misfolded B27-HC in the ...
Hui-Chun Yu, Kuang-Yung Huang, Ming-Chi Lu, Hsien-Lu Huang, Su-Qin Liu, Ning-Sheng Lai, Hsien-Bin Huang   +6 more
doaj   +1 more source

HLA-B27 Frequency and Clinical Correlates in Turkish Patients with Various Subtypes of Spondyloarthritis: A Single-Center Cohort Study

Namık Kemal Tıp Dergisi
Aim: This study aimed to evaluate the frequency of human leukocyte antigen (HLA)-B27 positivity and its clinical correlations in Turkish patients with ankylosing spondylitis (AS), psoriatic arthritis (PsA), inflammatory bowel disease (IBD)-associated ...
Dilara BULUT GÖKTEN, Hilmi TOZKIR, Ömer Atakan SOĞUR, Rıdvan MERCAN   +3 more
doaj   +1 more source

HLA B27 y las espondilartropatías seronegativas

Revista Cubana de Medicina, 1997
Se realizó el tipaje serológico para el antígeno HLA B27 a 19 pacientes con espondilartropatías seronegativas para conocer su relación y, de ellos, 6 resultaron positivos; 94 individuos sanos conformaron el grupo control y en 4 se encontró el antígeno ...
Modesto González Cortiñas, Lourdes Faurés Vergara, Ricardo Rodríguez Viera, Jesús Gómez Arbesú   +3 more
doaj  

CLINICAL COURSE OF JUVENILE IDIOPATHIC ARTHRITIS IN HLA-B27-POSITIVE PATIENTS IN ADULTHOOD

Медична наука України, 2017
Relevance. The existence of associations between histocompatibility antigens and JIA variants has been proved. There is no consensus that the JIAs associated with HLA-B27 antigen are transformed in adulthood into other diseases for which it is necessary ...
M.B. Dzhus, H.V. Mostbauer, T.A. Karasevska, O.I. Ivashkivsky   +3 more
doaj   +1 more source