Results 51 to 60 of about 499,322 (218)
Development and preliminary validation of the Early Sacroiliitis Screening Tool (ESHST), a dermatology‐oriented screening questionnaire for identifying hidradenitis suppurativa patients at increased risk of spondyloarthritis. ABSTRACT Background Hidradenitis suppurativa (HS) is increasingly recognized as a systemic inflammatory disease associated with ...
Umut Bakay +3 more
wiley +1 more source
The Oxidative Folding and Misfolding of Human Leukocyte Antigen-B27
The major histocompatibility complex class I molecule human leukocyte antigen (HLA)-B27 is strongly associated with a group of inflammatory arthritic disorders known as the spondyloarthropathies.
Guiliano, D.B. +4 more
core +1 more source
Background Human leukocyte antigen (HLA)-B27 is strongly associated with the development of reactive arthritis (ReA) in humans after salmonellosis. Human monocytic U937 cells transfected with HLA-B27 are less able to eliminate intracellular Salmonella ...
Hinton Jay CD +4 more
doaj +1 more source
A PD1‐CD137L fusion protein converts the immunoinhibitory PD‐L1 to an immunostimulatory signal and is more effective than targeting PD‐L1 and CD137 separately. ABSTRACT Tumour immune evasion frequently involves PD‐L1‐mediated inhibition of T cell activity, limiting the efficacy of PD1/PD‐L1 blockade, particularly in PD‐L1‐low or immunologically ‘cold ...
Runze Xia +10 more
wiley +1 more source
Rat models of autoimmune uveitis [PDF]
Experimental autoimmune uveitis ( EAU) in Lewis rats is a well-established model for human uveitis. During the last years we used this model to demonstrate extraocular induction of uveitis by antigenic mimicry of environmental antigens with retinal ...
Wildner, Gerhild +2 more
core +1 more source
A case of reactive arthritis after enteritis in in a 12-year-old boy [PDF]
Reactive arthritis comprises a subgroup within infection-associated arthritides in genetically susceptible hosts. Researchers and clinicians recognize two clinical forms of reactive arthritis which occurs after genitourinary tract infection and after ...
Peter Chun +3 more
doaj +1 more source
Mimicry of human histocompatibility HLA-B27 antigens by Klebsiella pneumoniae [PDF]
Anti-HLA-B27 monoclonal antibody M2, which was relatively specific for human histocompatibility antigen HLA-B27, was used to test several bacteria, some of which could potentially induce chronic arthritis in HLA-B27-positive individuals. Using the Western blot procedure, we observed positive reactions with 80,000- and 60,000-dalton antigens with one ...
M, Ogasawara, D H, Kono, D T, Yu
openaire +2 more sources
Prognostic prediction models for psoriatic arthritis in psoriasis: A systematic review
This systematic review evaluated prognostic prediction models used to assess the risk of future psoriatic arthritis in psoriasis patients. The included studies reported modest to moderate performance measures, with limited external validation, inadequate reporting and high risk of bias.
Fatimah Khoda +8 more
wiley +1 more source
Possession of the human leukocyte antigen (HLA) class I molecule B27 is strongly associated with ankylosing spondylitis (AS), but the pathogenic role of HLA-B27 is unknown.
Bowness, Paul, Bowness, P, Paul Bowness
core +1 more source
Objective: To determine prevalence of HLA-B27 among patients of spondyloarthropathies. Study Design: Cross sectional study. Place and Duration of Study: Department of Immunology, Armed Forces Institute of Pathology Rawalpindi Jan 2015 to Aug 2016 ...
Hamid Nawaz Tipu +1 more
doaj +2 more sources

