Results 31 to 40 of about 12,452 (175)
Altered regulation of ELAVL1/HuR in HLA-B27-expressing U937 monocytic cells. [PDF]
PLoS ONE, 2013 To investigate the role of HLA-B27 expression in the regulation of RNA binding protein (RBP) Embryonic Lethal Abnormal Vision (ELAV) L1/Human antigen R (HuR) expression in Salmonella-infected or LPS-stimulated human monocytic cells, since HuR is a ...
Anna S Sahlberg +3 more
doaj +1 more source
Cell Proliferation, EarlyView.Clinical‐grade HLA‐homozygous iPSC‐derived neural precursor cells restore motor function, rebuild striatal circuitry and reduce neuroinflammation in QA‐lesioned rats. These findings demonstrate robust neuronal replacement and microenvironment modulation, supporting their potential as a regenerative therapy for Huntington's disease.
Hyeonjoong Jeon +6 more
wiley +1 more source
Autoimmunity and Periodontitis
Journal of Periodontal Research, EarlyView.In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga +2 more
wiley +1 more source
BMC Genomics, 2010 Background Human leukocyte antigen (HLA)-B27 is strongly associated with the development of reactive arthritis (ReA) in humans after salmonellosis. Human monocytic U937 cells transfected with HLA-B27 are less able to eliminate intracellular Salmonella ...
Hinton Jay CD +4 more
doaj +1 more source
A case of reactive arthritis after enteritis in in a 12-year-old boy [PDF]
Korean Journal of Pediatrics, 2011 Reactive arthritis comprises a subgroup within infection-associated arthritides in genetically susceptible hosts. Researchers and clinicians recognize two clinical forms of reactive arthritis which occurs after genitourinary tract infection and after ...
Peter Chun +3 more
doaj +1 more source
Hla‐c locus antigens in hla‐b27 associated arthritis [PDF]
Arthritis & Rheumatism, 1978 AbstractFrequecies of the HLA‐C locus antigens, Cw 1, Cw2, Cw3, and Cw4, were determined in 88 patients with spondylitic diseases and 88 matched and 64 B27‐positive normal controls. Both Cw1 and Cw2 were significantly increased in B27‐positive patients and B27‐positive controls as compared to B27‐negative patients and matched controls.
F C, Arnett, M C, Hochberg, W B, Bias
openaire +2 more sources
Inflammatory Pseudotumor After Total Hip Arthroplasty‐An Increasingly Recognized Complication
Orthopaedic Surgery, EarlyView.This review systematically elucidates the clinical characteristics and management of inflammatory pseudotumor (IP) across different bearing surfaces, addressing a topic of increasing concern and providing a novel perspective. It synthesizes the five primary risk factors associated with IP, offering clinicians critical reference points.
Steve T. L. Pambayi +8 more
wiley +1 more source
Clinical Case Reports, Volume 14, Issue 6, June 2026.ABSTRACT Autoimmune hepatitis is a type of chronic hepatitis that is usually progressive, has unknown etiology, and can occur at any age. In the present case, drug‐associated autoimmune hepatitis (DIAIH) was discussed, and DIAIH secondary to isoniazid (INH) was found in two case reports in the literature.
Murat AY, Erhan Bozkurt
wiley +1 more source
Advanced Science, Volume 13, Issue 28, 18 May 2026.We identified GRIA2 as a critical driver of gastric cancer peritoneal metastasis through in vivo CRISPR screening. Mechanistically, GRIA2‐mediated calcium influx inhibits GSK3β and activates Wnt/β‐catenin signaling, driven by glutamate from cancer‐associated fibroblasts.
Jie Sun +13 more
wiley +1 more source
Histocompatibility HLA class I in anterior uveitis patients with and without spondyloarthritis
Современная ревматология, 2018 Anterior uveitis (AU) and ankylosing spondylitis (AS) are associated with histocompatibility human leukocyte antigen (HLA)-B27. Previous genetic studies conducted in different populations have also demonstrated other genetic associations, including HLA ...
I. A. Guseva +2 more
doaj +1 more source