The gut microbiome and HLA-B27-associated anterior uveitis: a case-control study
Background The human gut microbiome (GM) is involved in inflammation and immune response regulation. Dysbiosis, an imbalance in this ecosystem, facilitates pathogenic invasion, disrupts immune equilibrium, and potentially triggers diseases including ...
Sophia C. Morandi +7 more
doaj +1 more source
The rapid detection of human HLA-B*27 gene based on BASIC isothermal detection
Ankylosing spondylitis (AS) is a chronic, inflammatory arthritis of the spine and peripheral joints which is known to have a strong association with the human leukocyte antigen B27 (HLA-B27).
Ying Chen +9 more
doaj +1 more source
Background The human leukocyte antigen (HLA)-B27 gene is highly associated with ankylosing spondylitis (AS). However, not everyone who carries the HLA-B27 antigen develops AS, indicating that factors beyond the HLA-B27 gene contribute to the disease’s ...
Kuang-Hui Yu +5 more
doaj +1 more source
聚合酶链反应-直接测序法在强直性脊柱炎患者HLA-B27检测中的应用
目的探讨聚合酶链反应-直接测序法(polymerase chain reaction sequence-based typing,PCR-SBT)检测人类白细胞抗原B27(human leukocyte antigen B27,HLA-B27)在强直性脊柱炎(ankylosing spondylitis,AS)临床诊断中的价值。方法应用PCR-SBT法和临床常用的IMS-ELISA法对120例疑似AS患者外周血进行HLA-B27检测。以SPSS17 ...
王平均 +4 more
doaj
Seropositive rheumatoid arthritis with concomitant MRI confirmed sacroiliitis in an 18-year-old Saudi female: A case report of diagnostic and therapeutic challenges. [PDF]
Alenzi F, AlYamini S.
europepmc +1 more source
Saccular common iliac artery aneurysm associated with HLA-A26 and HLA-B27 in a young adult patient: a surgical case report and literature review. [PDF]
Yasumura H +7 more
europepmc +1 more source
Insights into axial spondyloarthritis features and the development of imaging evidence of sacroiliitis during long-term follow-up in routine clinical practice. [PDF]
Kieskamp SC +5 more
europepmc +1 more source
Axial spondyloarthritis patients with comorbid fibromyalgia feel worse, work less and more often try multiple biological therapies: results from a population-based, cross-sectional study investigating the discriminative capacity of pressure algometry. [PDF]
Brink A +8 more
europepmc +1 more source
Crohn's Disease and Axial Spondyloarthritis: From Systemic Inflammation to Amyloidosis. [PDF]
Kutsakina DA +10 more
europepmc +1 more source

