Results 1 to 10 of about 118,027 (327)

Biology and therapeutic potential of mesenchymal stem cell extracellular vesicles in axial spondyloarthritis

open access: yesCommunications Biology, 2023
Axial spondyloarthritis (AxSpA) is a chronic, inflammatory, autoimmune disease that predominantly affects the joints of the spine, causes chronic pain, and, in advanced stages, may result in spinal fusion.
Fataneh Tavasolian, Robert D. Inman
doaj   +1 more source

HLA-B27 is associated with reduced disease activity in axial spondyloarthritis

open access: yesScientific Reports, 2021
HLA-B27 is associated with increased susceptibility and disease activity of ankylosing spondylitis, but the effect of HLA-B27 on the activity of the broader category now called axial spondyloarthritis (AxSpA) is apparently the opposite.
James T. Rosenbaum   +9 more
doaj   +1 more source

Pyogenic Spondylitis [PDF]

open access: yesActa Orthopaedica Scandinavica, 1978
During the period 1972-1974 10 patients suffering from pyogenic spondylitis have been treated at the Central Hospital of Middle Finland. Three of the patients had become acutely ill with septic fever and back pain. In the remaining cases the onset of the disease was insidious. Fever, weight loss and fatigue were the general symptoms.
E, Partio, S, Hatanpää, P, Rokkanen
openaire   +3 more sources

Candidal Vertebral Osteomyelitis in the Midst of Renal Disorders [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Vertebral osteomyelitis also known as discitis/pyogenic spondylitis refers to inflammation of the vertebral disc space. It is commonly seen in men and adults more than 50 years of age.
Anusha Gopinathan   +4 more
doaj   +1 more source

Interleukin 17A inhibitor secukinumab in the treatment of patients with psoriatic arthritis

open access: yesKlinicist, 2022
Psoriatic arthritis (PsA) is a chronic inflammatory joint disease associated with psoriasis and characterized by various presentation, course, and response to treatment.
N. A. Shostak   +4 more
doaj   +1 more source

Efficacy and safety of ixekizumab through 52 weeks in two phase 3, randomised, controlled clinical trials in patients with active radiographic axial spondyloarthritis (COAST-V and COAST-W). [PDF]

open access: yes, 2020
OBJECTIVES: To investigate the efficacy and safety of ixekizumab for up to 52 weeks in two phase 3 studies of patients with active radiographic axial spondyloarthritis (r-axSpA) who were biological disease-modifying antirheumatic drug (bDMARD)-naive ...
Baraliakos, X.   +19 more
core   +3 more sources

Diagnosis of Spinal Infection with Alpha-defensin Lateral Flow Test: A Preliminary Report

open access: yesSpine Surgery and Related Research, 2022
Introduction: The alpha-defensin lateral flow test has been used in periprosthetic joint infection as a diagnostic support tool because of its simplicity and speed. However, the test has not been used to diagnose spinal infections.
Atsuhiro Yoshida   +5 more
doaj   +1 more source

Clinical profile, diagnosis, treatment, and outcome of patients with tubercular versus nontubercular causes of spine involvement: A retrospective cohort study from India

open access: yesInternational Journal of Mycobacteriology, 2022
Background: In tuberculosis (TB) endemic areas, other pyogenic causes of spine involvement may be missed. The study aimed to describe TB and non-TB causes of spine involvement and identify features that can help in differentiating them.
Nitin Gupta   +9 more
doaj   +1 more source

Disease and psychological status in ankylosing spondylitis. [PDF]

open access: yes, 2006
Objectives. Psychological factors may be important in the assessment and management of ankylosing spondylitis (AS). Our primary objective was to describe associations between disease and psychological status in AS, using AS-specific assessment tools and ...
Goodacre, J. A.   +5 more
core   +1 more source

Spine Fractures of Patients with Ankylosing Spondylitis and Diffuse Idiopathic Skeletal Hyperostosis: Fracture Severity and Injury-Related Mortality at a Level I Trauma Center [PDF]

open access: yesAsian Spine Journal, 2023
Study Design Retrospective review of prospectively collected cohort. Purpose To identify differences in treatment and mortality of spine fractures in patients with ankylosing conditions of the spine. Overview of Literature Ankylosing spondylitis (AS) and
Stephen Ryan Chen   +9 more
doaj   +1 more source

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