Abstract Many patients with inflammatory bowel disease (IBD) do not adequately respond to infliximab, potentially due to individual differences in pharmacokinetics (PK). This study aimed to identify clinical and biochemical variables associated with infliximab PK.
Ilse A. Pool +6 more
wiley +1 more source
Patient-tailored training programme on cardiorespiratory fitness, trunk strength and mobility leads to significantly better outcomes in individuals with axial spondyloarthritis. [PDF]
De Mits S +7 more
europepmc +1 more source
R, Bennett, E G, Bywaters, P J, Holt
openaire +2 more sources
Epiglottic Ulceration as an Initial Manifestation of Crohn's Disease
ABSTRACT Crohn's disease can present with various extraintestinal symptoms; however, laryngeal involvement, particularly epiglottic ulcers, is rare. A 52‐year‐old man presented with a sore throat. Laryngeal endoscopy revealed an epiglottic ulcer. He had no gastrointestinal symptoms.
Niina Yamashita +2 more
wiley +1 more source
Comparison of radiographic spinal changes and their progression in patients with axial spondyloarthritis vs. psoriatic arthritis with inflammatory axial involvement. [PDF]
Sewerin P +8 more
europepmc +1 more source
Abstract Objectives Inflammatory bowel disease (IBD) constitutes a challenging and long‐lasting burden for pediatric patients. The management of IBD is multifaceted involving conventional medication but also dietary measures. An increasing number of patients are turning to complementary and alternative medicine (CAM) in their quest to alleviate IBD ...
Katharina Guilcher +12 more
wiley +1 more source
Posterior percutaneous fixation without anterior or posterior debridement for infectious spondylitis in high-morbidity patients: A retrospective comparative study. [PDF]
Lee CY, Kim SK, Seo HY.
europepmc +1 more source
Pharmacokinetic Model Selection for Personalized Infliximab Dosing in IBD
ABSTRACT Infliximab, a monoclonal antibody used for immune‐mediated diseases, shows high interpatient pharmacokinetic variability. Prolonged exposure increases the risk of adverse effects and costs, making dose personalization essential to balance safety, efficacy, and cost‐effectiveness. Population pharmacokinetic models support individualized dosing,
Sahira Chaiben +4 more
wiley +1 more source
Alterations in the Gut Microbiome in Ankylosing Spondylitis and Their Correlation with Disease Activity. [PDF]
Jeong H +12 more
europepmc +1 more source

