Results 211 to 220 of about 151,084 (348)
• SHP2 deficiency in T cells could alleviate both psoriasis‐like skin lesion and adoptive transfer colitis. • SHP2 deficiency in T cells promotes the differentiation toward Treg, thus regulating the balance of Th17/Treg. • SHP2 may become a promising common therapeutic target in the treatment of autoimmune diseases.
Shuqiong Zhang+7 more
wiley +1 more source
Mechanisms of musculoskeletal consequences of COVID-19
Introduction A coronavirus, SARS-CoV-2, called COVID-19 by the WHO has caused a pandemic of respiratory illness killed more than 6 million people. The severe infection has a significant negative impact on the entire musculoskeletal system.
Natalya N. Grigorieva+1 more
doaj +1 more source
The retrospective study of surgical treatment of 463 tuberculosis spondylitis patients having 745 surgical operations has been conducted. Post-surgery complications have been found in 96 (12.9%) patients.
S. V. Burlakov+2 more
doaj
Fat Fraction and Iron Concentration in Lumbar Vertebral Bone Marrow in the UK Biobank
ABSTRACT Background Vertebral bone marrow (VBM) plays a critical role in bone homeostasis and metabolic health. Alterations in VBM fat and iron composition have been linked to age‐related metabolic and musculoskeletal disorders, yet remain underexplored in large population‐based studies. Objectives This study aimed to assess VBM adipose tissue and iron
James R. Parkinson+5 more
wiley +1 more source
Ankylosing Spondylitis and Chronic Inflammatory Diseases of the Intestines [PDF]
J. A. McBride+4 more
openalex +1 more source
ABSTRACT Alzheimer's disease (AD) is a complex and multifactorial neurodegenerative disorder, recognized as the most prevalent form of dementia. It is characterized by multiple pathological processes, including amyloid‐beta accumulation, neurofibrillary tangles, and neuroinflammation. The therapeutic efficacy of traditional single‐target drugs has been
Md Saad Hossain, Md Hamed Hussain
wiley +1 more source
Genetically predicted ankylosing spondylitis increases the risk of heart failure: a Mendelian randomization study. [PDF]
Liu C+8 more
europepmc +1 more source
Prescribing Inflammatory Bowel Disease Medications in Chronic Kidney Disease: A Practical Guide
Most therapies used in inflammatory bowel disease appear safe and effective when used in chronic kidney disease including on renal replacement therapy, particularly biologic therapies. Some caution should be considered when using conventional therapies and JAK inhibitors.
Lynna Chen+6 more
wiley +1 more source