Results 211 to 220 of about 151,084 (348)

T Cell‐Specific Deficiency of Src Homology 2‐Containing Protein Tyrosine Phosphatase 2 Ameliorates Psoriasis and Colitis by Promoting Treg Differentiation

open access: yesMedComm, Volume 6, Issue 8, August 2025.
• SHP2 deficiency in T cells could alleviate both psoriasis‐like skin lesion and adoptive transfer colitis. • SHP2 deficiency in T cells promotes the differentiation toward Treg, thus regulating the balance of Th17/Treg. • SHP2 may become a promising common therapeutic target in the treatment of autoimmune diseases.
Shuqiong Zhang   +7 more
wiley   +1 more source

Mechanisms of musculoskeletal consequences of COVID-19

open access: yesГений oртопедии
Introduction A coronavirus, SARS-CoV-2, called COVID-19 by the WHO has caused a pandemic of respiratory illness killed more than 6 million people. The severe infection has a significant negative impact on the entire musculoskeletal system.
Natalya N. Grigorieva   +1 more
doaj   +1 more source

IMPACT OF PERIOPERATIVE RISK FACTORS ON THE FORMATION OF INFECTIOUS COMPLICATIONS OF SURGICAL TREATMENT OF TUBERCULOSIS SPONDYLITIS

open access: yesТуберкулез и болезни лёгких, 2015
The retrospective study of surgical treatment of 463 tuberculosis spondylitis patients having 745 surgical operations has been conducted. Post-surgery complications have been found in 96 (12.9%) patients.
S. V. Burlakov   +2 more
doaj  

The cataract response in Radium-224 patients [PDF]

open access: yes, 1989
Chmelevsky, D.   +5 more
core   +1 more source

Fat Fraction and Iron Concentration in Lumbar Vertebral Bone Marrow in the UK Biobank

open access: yesObesity Science &Practice, Volume 11, Issue 4, August 2025.
ABSTRACT Background Vertebral bone marrow (VBM) plays a critical role in bone homeostasis and metabolic health. Alterations in VBM fat and iron composition have been linked to age‐related metabolic and musculoskeletal disorders, yet remain underexplored in large population‐based studies. Objectives This study aimed to assess VBM adipose tissue and iron
James R. Parkinson   +5 more
wiley   +1 more source

Ankylosing Spondylitis and Chronic Inflammatory Diseases of the Intestines [PDF]

open access: green, 1963
J. A. McBride   +4 more
openalex   +1 more source

Multi‐Target Drug Design in Alzheimer's Disease Treatment: Emerging Technologies, Advantages, Challenges, and Limitations

open access: yesPharmacology Research &Perspectives, Volume 13, Issue 4, August 2025.
ABSTRACT Alzheimer's disease (AD) is a complex and multifactorial neurodegenerative disorder, recognized as the most prevalent form of dementia. It is characterized by multiple pathological processes, including amyloid‐beta accumulation, neurofibrillary tangles, and neuroinflammation. The therapeutic efficacy of traditional single‐target drugs has been
Md Saad Hossain, Md Hamed Hussain
wiley   +1 more source

Genetically predicted ankylosing spondylitis increases the risk of heart failure: a Mendelian randomization study. [PDF]

open access: yesFront Cardiovasc Med
Liu C   +8 more
europepmc   +1 more source

Prescribing Inflammatory Bowel Disease Medications in Chronic Kidney Disease: A Practical Guide

open access: yesAlimentary Pharmacology &Therapeutics, Volume 62, Issue 4, Page 400-418, August 2025.
Most therapies used in inflammatory bowel disease appear safe and effective when used in chronic kidney disease including on renal replacement therapy, particularly biologic therapies. Some caution should be considered when using conventional therapies and JAK inhibitors.
Lynna Chen   +6 more
wiley   +1 more source

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