Results 41 to 50 of about 151,084 (348)

Secukinumab, an Interleukin-17A Inhibitor, in Ankylosing Spondylitis.

New England Journal of Medicine, 2015
BACKGROUND Secukinumab is an anti-interleukin-17A monoclonal antibody that has been shown to control the symptoms of ankylosing spondylitis in a phase 2 trial. We conducted two phase 3 trials of secukinumab in patients with active ankylosing spondylitis.
D. Baeten, J. Sieper, J. Braun, X. Baraliakos, M. Dougados, P. Emery, A. Deodhar, B. Porter, R. Martin, M. Andersson, S. Mpofu, H. Richards   +11 more
semanticscholar   +1 more source

Association of Secukinumab Treatment With Tuberculosis Reactivation in Patients With Psoriasis, Psoriatic Arthritis, or Ankylosing Spondylitis

JAMA dermatology, 2020
This pooled cohort study evaluates the safety of newer biological agents for the treatment of tuberculosis infection and activation in patients with psoriasis, psoriatic arthritis, and ankylosing spondylitis.
B. Elewski, J. Baddley, A. Deodhar, M. Magrey, P. Rich, E. Soriano, J. Soung, W. Bao, D. Keininger, K. Marfo, M. Patekar, Abhishek Sharma, A. Shete, M. Lebwohl   +13 more
semanticscholar   +1 more source

Physical activity and sedentary behaviour and their associations with clinical measures in axial spondyloarthritis [PDF]

, 2019
Engaging in physical activity (PA) is a key aspect in the management of axial spondyloarthritis (axial SpA), however, its relationship with clinical measures is unknown.
Cameron, Sara, Coulter, Elaine, McDonald, Marie Therese, Paul, Lorna, Siebert, Stefan   +4 more
core   +3 more sources

Treating spondyloarthritis, including ankylosing spondylitis and psoriatic arthritis, to target: recommendations of an international task force [PDF]

, 2013
Background: Therapeutic targets have been defined for diseases like diabetes, hypertension or rheumatoid arthritis and adhering to them has improved outcomes. Such targets are just emerging for spondyloarthritis (SpA). Objective: To define the treatment
Baraliakos, Xenofon, Betteridge, Neil, Braun, Jürgen, Burgos-Vargas, Ruben, Collantes-Estevez, Eduardo, de Wit, Martinus, Deodhar, Atul, Dougados, Maxime, Elewaut, Dirk, Emery, Paul, FitzGerald, Oliver, Gossec, Laure, Helliwell, Philip, Jongkees, Merryn, Kavanaugh, Arthur, Kvien, Tore K, Landewé, Robert, Luger, Thomas, Maccarone, Mara, Mease, Philip, Olivieri, Ignazio, Redlich, Kurt, Reveille, John, Ritchlin, Christopher, Rudwaleit, Martin, Schoels, Monika, Sieper, Joachim, Smolen, Josef S, Van den Bosch, Filip, van der Heijde, Désirée, Wei, James Cheng-Chung, Winthrop, Kevin   +31 more
core   +2 more sources

Birth Outcomes and Disease Activity During Pregnancy in a Prospective Cohort of Women With Psoriatic Arthritis and Ankylosing Spondylitis

Arthritis care & research, 2020
To add to data on adverse birth outcomes accounting for disease activity in women with psoriatic arthritis (PsA) and ankylosing spondylitis (AS).
Chelsey J. F. Smith, G. Bandoli, A. Kavanaugh, C. Chambers   +3 more
semanticscholar   +1 more source

Tuberculous spondylitis presenting as severe chest pain

Clinics and Practice, 2012
This case report describes a 32-year-old male who presented to an emergency department with severe chest pain and a history of cough, fever, night sweats, loss of appetite and weight.
Martha A. Kaeser, Norman W. Kettner, Usama Albastaki, Hossam Ahmed Kotb, Ibrahim M.A. Eldesouky, Claude Pierre-Jerome   +5 more
doaj   +1 more source

Patient perspectives of managing fatigue in ankylosing spondylitis, and views on potential interventions: a qualitative study [PDF]

, 2013
<p>Background: Fatigue is a major component of living with ankylosing spondylitis (AS), though it has been largely over-looked, and currently there are no specific agreed management strategies.</p> <p>Methods: This qualitative ...
A Calin, A van Tubergen, B Belza, D Cote-Arsenault, E Dernis-Labous, Elizabeth Irvine, H Dagfinrud, H Repping-Wuts, Helen Davies, J Kabat-Zinn, J Kabat-Zinn, J Trendall, KGA Adams, MD Atkinson, MG Swain, Michael Dennis, MM Ward, MP Davis, N Aissaoui, National Institute for Health and Clinical Excellence, P Burnard, P Grossman, R Gunaydin, RE Boyatzis, Roxanne Cooksey, S Brophy, S Council:, S Garrett, S Hewlett, S Hultgren, SC Richards, SD Jones, SDH Brophy, Sinead Brophy, Stefan Siebert, Welsh Assembly Government, WH Koh, Y Ibn Yacoub, Y Turan   +38 more
core   +2 more sources

Clinical Effect of Doxycycline Combined with Compound Sulfamethoxazole and Rifampicin in the Treatment of Brucellosis Spondylitis

Drug Design, Development and Therapy, 2021
Xin-Ming Yang, Yong-Li Jia, Ying Zhang, Pei-Nan Zhang, Yao Yao, Yan-Lin Yin, Ye Tian Department of Orthopaedics, The First Affiliated Hospital of Hebei North University, Zhangjiakou, 075000, Hebei, People’s Republic of ChinaCorrespondence: Xin-Ming ...
Yang XM, Jia YL, Zhang Y, Zhang PN, Yao Y, Yin YL, Tian Y   +6 more
doaj  

Neutrophil/lymphocyte and platelet/lymphocyte ratios as potential markers of disease activity in patients with Ankylosing spondylitis: a case-control study

Advances in Rheumatology, 2020
Background The neutrophil/ lymphocyte ratio (NLR) and platelet/lymphocyte ratio (PLR) have the potential to be inflammatory markers that reflect the activity of many inflammatory diseases.
M. H. Al-Osami, N. Awadh, Khalid Burhan Khalid, A. Awadh   +3 more
semanticscholar   +1 more source

Application of negative pressure wound therapy in the treatment of pyoinflammatory complications after spinal surgery

Хирургия позвоночника, 2017
Objective. To analyze the first experience of negative pressure wound therapy in the treatment of patients with infectious complications after surgical interventions on the spine. Material and Methods. Clinical cases of negative pressure wound therapy
Aleksandr K. Dulaev, Vadim A. Manukovsky, Sergey A. Shlyapnikov, Takhir I. Tamaev, Vladimir A. Manukovsky, Ildar M. Batyrshin, Yury V. Belyakov, Valery V. Serikov, Irina S. Afanasyeva   +8 more
doaj   +1 more source