Results 121 to 130 of about 76,712 (310)

Diagnostic accuracy of inflammatory back pain for axial spondyloarthritis in rheumatological care [PDF]

, 2018
Objective: Inflammatory back pain (IBP), the key symptom of axial spondyloarthritis (axSpA), including ankylosing spondylitis, has been proposed as a screening test for patients presenting with chronic back pain in primary care.
Braun, Juergen, Callhoff, Johanna, Listing, Joachim, Poddubnyy, Denis, Rudwaleit, Martin, Sieber, Joachim, Spiller, Inge   +6 more
core   +1 more source

Evaluating Associations Between Ankylosing Spondylitis, Torque Teno Virus and Polymorphisms in Interleukin 6 and Vitamin D Receptor Genes

International Journal of Immunogenetics, EarlyView.
ABSTRACT The etiology of ankylosing spondylitis (AS) is complex and not yet fully understood. Interleukin‐6 (IL‐6), vitamin D and the vitamin D receptor (VDR) play an important role in modulating immune response, and Torque teno virus is considered a marker of immune status. This case–control study aimed to investigate the predisposition to AS. A total
Dănuț Cimponeriu, Lavinia‐Mariana Berca, Irina Radu, Mihai Toma, Remus Nica, Silvia Nica, Roxana Măciucă   +6 more
wiley   +1 more source

Spondüloartriidi nüüdisaegne käsitlus [PDF]

, 2016
Spondüloartriidi käsitluses on viimase kümnendi jooksul toimunud olulised muutused, mille ajendiks on olnud vajadus diagnoosida põletikulisi seljahaigusi kiiremini ja alustada varem ravi.
Kallikorm, Riina, Ulst, Katrin
core   +2 more sources

Efficacy and safety of brodalumab in palmoplantar pustulosis: A 68‐week randomized Phase 3 trial

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This open‐label study is a continuation of the 16‐week double‐blind, Phase 3 trial assessing the efficacy and safety of brodalumab 210 mg subcutaneously, till a 68‐week extension period. Continued improvement was seen in the PPPASI 50/75/90 responses, PPPSI scores, PGA 0/1 responses and DLQI. Abstract Background The efficacy and safety of brodalumab in
Masamoto Murakami, Yukari Okubo, Satomi Kobayashi, Natsuko Kikuta, Yoshiumi Ouchi, Kenta Shishido, Tadashi Terui   +6 more
wiley   +1 more source

Gut Microbiome and Its Interaction with Immune System in Spondyloarthritis

Microorganisms, 2020
Emerging evidence suggests there is a gut-joint axis in spondyloarthritis (SpA). In a study, subclinical gut inflammation occurred in nearly 50% of SpA. Chronic gut inflammation also correlated with disease activity in SpA.
Jacqueline So, Lai-Shan Tam
doaj   +1 more source

The effect of cigarette smoke exposure on the development of inflammation in lungs, gut and joints of TNFΔARE mice [PDF]

, 2015
The inflammatory cytokine TNF-alpha is a central mediator in many immune-mediated diseases, such as Crohn's disease (CD), spondyloarthritis (SpA) and chronic obstructive pulmonary disease (COPD).
A Churg, A I D'Hulst, A I D'Hulst, A Oberholzer, AN Ananthakrishnan, B Chassaing, BR Vuillemenot, C Ott, Claude A. Cuvelier, D Kontoyiannis, D Kontoyiannis, D Laukens, D Laukens, D Poddubnyy, D Poddubnyy, D Raddatz, D Wendling, Debby Laukens, Dirk Elewaut, E Perry, EM Thomson, G Kollias, G Macdonald, Griet Conickx, Guy F. Joos, Guy G. Brusselle, H Roberts, HS Hreggvidsdottir, J Bagaitkar, J Callhoff, J George, J Karczewski, JC Peng, JJ Peschon, K Chang, K Vermaelen, KA Papadakis, Karlijn Debusschere, Ken R. Bracke, KR Bracke, L Allais, L Arcavi, L Klareskog, Liesbeth Allais, LK Lundblad, LL Dupont, M De Vos, M Montbarbon, Martine De Vos, MF Neurath, P Jacques, P Jacques, P Vassalli, PG Persson, R Matsuda, R Vlahos, R Vlahos, Rebecca De Smet, S Mukhopadhyay, S Suissa, S Tangedal, S Verschuere, S Verschuere, Selvakumar Subbian, SK Biswas, Smitha Kumar, Stephanie Verschuere, Tania Maes, W Strober, Y Arnson   +69 more
core   +3 more sources

Prevalence and impact of comorbidities in axial spondyloarthritis: systematic review and meta-analysis

Rheumatology, 2020
Objectives Comorbidities are common in people with axial spondyloarthritis (axSpA). In this systematic review and meta-analysis, we aimed to: (i) describe the prevalence of commonly reported comorbidities, (ii) compare comorbidities between axSpA and ...
S. Zhao, S. Robertson, T. Reich, N. Harrison, R. Moots, N. Goodson   +5 more
semanticscholar   +1 more source

Delphi consensus: First‐line use of biologics and small molecules in hidradenitis suppurativa

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This Delphi Consensus study identified upgrade criteria for the use of biologics and small molecules as first‐line therapy in hidradenitis suppurativa (HS). European HS experts evaluated 16 clinical scenarios, voting on eligibility for therapy escalation.
Georgios Nikolakis, Erkan Alpsoy, Florian Anzengruber, Matthias Augustin, Falk G. Bechara, Pierre‐André Becherel, Farida Benhadou, Vincenzo Bettoli, Joana Cabete, Raffaele Dante Caposiena Caro, Antonella Di Cesare, Giovanni Damiani, Valentina Dini, Evangelos J. Giamarellos‐Bourboulis, Krisztián Gáspár, Katalin Glasenhardt, Philippe Guillem, Ariela Hafner, Barbara Horvath, John R. Ingram, Vaiva Jarienè, Gregor B. E. Jemec, Alexander Katoulis, Natalia Kirsten, Georgios Kokolakis, Piotr K. Krajewski, Aikaterini I. Liakou, Flavia Manzo Margiotta, Angelo V. Marzano, Antonio Martorell, Lukasz Matusiak, Dillon Mintoff, Alejandro Molina Leyva, Andreas Pinter, Anna Pirogova, Maurizio Podda, Francesca Prignano, Jorge Romani, Marco Romanelli, Elia Rosi, Samed Sahin, Ditte M. L. Saunte, Sylke Schneider‐Burrus, Mariano Suppa, Jacek Szepietowski, Andrea Szegedi, Simon Francis Thomsen, Thrasyvoulos Tzellos, Anastasia Trigoni, Hessel H. Van Der Zee, Kelsey Van Straalen, Skaidra Valiukevičiene, Eva Vilarrasa, Esther von Stebut, Christos C. Zouboulis   +54 more
wiley   +1 more source

A Case of a Non-Radiographic Axial Spondyloarthritis in a 14-Year-Old Girl Presenting with Muscle Weakness and Hyperthyroidism

International Medical Case Reports Journal, 2020
Abdullah Elhosiny,1 Renad Alshoubaki,1 Lama Sindi,2 Sadeem Bukhari,2 Hani Almoallim1,2 1Department of Medicine, Dr. Soliman Fakeeh Hospital, Jeddah, Saudi Arabia; 2Department of Medicine, Faculty of Medicine, Umm Alqura University, Makkah, Saudi ...
Elhosiny A, Alshoubaki R, Sindi L, Bukhari S, Almoallim H   +4 more
doaj  

Targeting inflammatory pathways in axial spondyloarthritis. [PDF]

, 2019
The triggers and pathogenesis of axial spondyloarthritis (axSpA) are not yet completely understood. However, therapeutic agents targeting tumor necrosis factor-α and interleukin-17 inflammatory pathways have proven successful in suppressing many of the ...
Furst, Daniel E, Louie, James S
core