Results 51 to 60 of about 63,084 (277)

Differences between radiographic and non-radiographic axial spondyloarthritis patients in a Mexican cohort

Scientific Reports
To compare the demographic, clinical, and laboratory characteristics, disease onset, and clinical features of radiographic axial Spondyloarthritis (r-axSpA) and non-radiographic axial Spondyloarthritis (nr-axSpA) patients.
John Londono, Cesar Pacheco-Tena, Ana Maria Santos, Mario Humberto Cardiel, Gustavo Rodríguez-Salas, Igor Rueda, Sofía Arias-Correal, Cristian Mesa, Mantilla Marta Juliana, Juan Camilo Santacruz, Juan Camilo Rueda, Gilberto Vargas-Alarcón, Rubén Burgos-Vargas   +12 more
doaj   +1 more source

Safety of Prescription Nonsteroidal Anti‐inflammatory Drugs in Adults with Inflammatory Bowel Disease: Data from a Large Administrative Claims Cohort

Arthritis Care &Research, Accepted Article.
Objectives The concern that nonsteroidal anti‐inflammatory drugs (NSAIDs) may precipitate flares of inflammatory bowel disease (IBD) has limited their use in managing musculoskeletal symptoms in this population, but safety data are mixed. Methods This retrospective cohort study included patients with IBD ≥ 18 years of age from Optum's de‐identified ...
Adam S. Mayer, Rui Xiao, Meenakshi Bewtra, Michael D. George, Pamela F. Weiss   +4 more
wiley   +1 more source

Elevating the Standard of Care for Patients with Axial Spondyloarthritis: ‘Calls to Action’ from Rheumacensus, a Multistakeholder Pan-European Initiative

Rheumatology and Therapy
Introduction Several barriers to optimal care in axial spondyloarthritis (axSpA) exist, which is detrimental to patient outcomes. The Rheumacensus programme aimed to identify how the standard of care (SoC) and treatment ambition for patients with axSpA ...
Andri Phoka, Bart J. F. van den Bemt, Ennio Lubrano, Inderjit Singh, Cristina Fernández-Carballido, Detlev Parow, Dale Webb, Fabienne Lacombe, Laura Harrington, Xenofon Baraliakos   +9 more
doaj   +1 more source

Expression analysis of HLA-E and NKG2A and NKG2C receptors points at a role for natural killer function in ankylosing spondylitis [PDF]

, 2018
Background. Ankylosing Spondylitis (AS) is a complex chronic inflammatory disease strongly associated with the majority of HLA-B27 alleles. HLA-E are non-classical MHC class I molecules that specifically interact with the natural killer receptors NKG2A ...
Angioni, Mm, Cauli, A, Congia, M, Dessole, G, Fiorillo, Mt, Floris, A, Mascia, E, Mathieu, A., Paladini, F, Piga, M, Pinna, S, Sorrentino, R, Tedeschi, V   +12 more
core   +1 more source

Real‐world trends in prenatal antirheumatic drug utilization in Ontario, Canada: A cross‐sectional time‐series analysis

Arthritis Care &Research, Accepted Article.
Objectives This study aimed to describe real‐world trends in preconception and prenatal use of antirheumatic drugs among pregnant individuals with rheumatic diseases in Ontario, Canada. Methods We conducted a time‐series analysis using repeated cross‐sectional data to examine annual patterns of disease‐modifying antirheumatic drug (DMARD) use among ...
Shenthuraan Tharmarajah, Swaleh Hussain, Sara J.T. Guilcher, Lisa M. McCarthy, Dharini Mahendira, Howard Berger, Mina Tadrous   +6 more
wiley   +1 more source

Biomarkers in Inflammatory Bowel Disease-Associated Spondyloarthritis: State of the Art and Unmet Needs

Journal of Immunology Research, 2019
Inflammatory bowel disease-associated spondyloarthritis is a systemic disease characterized by the chronic inflammation of both the gastrointestinal tract and the musculoskeletal system.
Devis Benfaremo, Michele Maria Luchetti, Armando Gabrielli   +2 more
doaj   +1 more source

Silencing SOCS3 Markedly Deteriorates Spondyloarthritis in Mice Induced by Minicircle DNA Expressing IL23

Frontiers in Immunology, 2018
Objective: Despite extensive studies, the precise mechanism underlying spondyloarthritis, especially ankylosing spondylitis, remains elusive. This study aimed to develop an ideal animal model for an insight into mechanism of spondyloarthritis and ...
Yuhai Chen, Jing Ouyang, Ruoxiang Yan, Mohamed Hassan Maarouf, Mohamed Hassan Maarouf, Mohamed Hassan Maarouf, Xuefei Wang, Xuefei Wang, Biao Chen, Biao Chen, Shasha Liu, Shasha Liu, Jiayue Hu, Guijie Guo, Jing Zhang, Sheng-Ming Dai, Huji Xu, Ji-Long Chen   +17 more
doaj   +1 more source

Enthesopathy in spondyloarthritis: the literature review

Научно-практическая ревматология, 2021
The article presents data on epidemiology, pathogenesis, clinical manifestations, diagnosis and therapy of enthesopathy in spondyloarthritis. The approaches to assessment of this pathology are examined and detailed, modern clinical and ultrasound indices
D. I. Abdulganieva, E. R. Kirillova, I. F. Fairushina, G. R. Gaynullina, R. Z. Abdrakipov, R. G. Mukhina, E. I. Mukhametshina   +6 more
doaj   +1 more source

Uveitis in spondyloarthritis [PDF]

Therapeutic Advances in Musculoskeletal Disease, 2020
Uveitis is the most frequent extra-articular manifestation of axial spondyloarthritis (SpA), occurring in up to one-third of the patients. In the majority of patients, uveitis is acute, anterior and unilateral and presents with photosensitivity, sudden onset of pain and blurred vision. Topical steroids are an effective treatment; however, recurrent or
Judith Rademacher, Denis Poddubnyy, Uwe Pleyer   +2 more
openaire   +3 more sources

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source