Results 71 to 80 of about 56,684 (289)

Original paper Cytokine profiles in axial spondyloarthritis

, 2015
Objectives: Current studies concentrate on the cytokine network and its role in the pathogenesis of spondyloarthritis (SpA). In this study, we analyzed whether the serum cytokine profile (interleukins: IL-10, IL-11, IL-12, IL-15, IL-17, IL-23 and IL-33)
Marta Madej, Piotr Wiland, Beata Nowak, Arkadiusz Chlebicki, Lucyna Korman, Łukasz Lubiński, Jerzy Świerkot, Renata Sokolik, Patryk Woytala   +8 more
core   +1 more source

Diagnosis, monitoring, and management of axial spondyloarthritis

Rheumatology International
Axial spondyloarthritis (axSpA) is a chronic condition predominantly affecting the spine and sacroiliac joints. This article provides an in-depth overview of the current approaches to diagnosing, monitoring, and managing axSpA, including insights into ...
O. Zimba, B. Koçyiğit, Mariusz Korkosz
semanticscholar   +1 more source

Efficacy of a tight-control and treat-to-target strategy in axial spondyloarthritis: results of the open-label, pragmatic, cluster-randomised TICOSPA trial

Annals of the Rheumatic Diseases, 2021
Objectives To compare the benefits of a tight-control/treat-to-target strategy (TC/T2T) in axial spondyloarthritis (axSpA) with those of usual care (UC). Methods Pragmatic, prospective, cluster-randomised, controlled, open, 1-year trial (NCT03043846). 18
A. Moltó, C. López-Medina, F. E. Van den Bosch, A. Boonen, C. Webers, E. Dernis, F. V. van Gaalen, M. Soubrier, P. Claudepierre, A. Baillet, M. Starmans-Kool, A. Spoorenberg, P. Jacques, P. Carron, R. Joos, J. Lenaerts, L. Gossec, S. Pouplin, A. Ruyssen-witrand, L. Sparsa, A. V. van Tubergen, D. M. van der Heijde, M. Dougados   +22 more
semanticscholar   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Elevating the Standard of Care for Patients with Axial Spondyloarthritis: ‘Calls to Action’ from Rheumacensus, a Multistakeholder Pan-European Initiative

Rheumatology and Therapy
Introduction Several barriers to optimal care in axial spondyloarthritis (axSpA) exist, which is detrimental to patient outcomes. The Rheumacensus programme aimed to identify how the standard of care (SoC) and treatment ambition for patients with axSpA ...
Andri Phoka, Bart J. F. van den Bemt, Ennio Lubrano, Inderjit Singh, Cristina Fernández-Carballido, Detlev Parow, Dale Webb, Fabienne Lacombe, Laura Harrington, Xenofon Baraliakos   +9 more
doaj   +1 more source

Treating axial spondyloarthritis and peripheral spondyloarthritis, especially psoriatic arthritis, to target: 2017 update of recommendations by an international task force

Annals of the Rheumatic Diseases, 2017
Therapeutic targets have been defined for axial and peripheral spondyloarthritis (SpA) in 2012, but the evidence for these recommendations was only of indirect nature. These recommendations were re-evaluated in light of new insights. Based on the results
J. Smolen, Monika Schöls, J. Braun, M. Dougados, O. FitzGerald, D. Gladman, A. Kavanaugh, R. Landewé, P. Mease, J. Sieper, T. Stamm, M. D. de Wit, D. Aletaha, X. Baraliakos, N. Betteridge, F. E. Van den Bosch, L. Coates, P. Emery, L. Gensler, L. Gossec, P. Helliwell, Merryn Jongkees, T. Kvien, R. Inman, I. McInnes, M. Maccarone, P. Machado, A. Moltó, A. Ogdie, D. Poddubnyy, C. Ritchlin, M. Rudwaleit, A. Tanew, B. Thio, D. Veale, K. de Vlam, D. M. van der Heijde   +36 more
semanticscholar   +1 more source

Radiographic Progression in Sacroiliac Joints in Patients With Axial Spondyloarthritis: Results From a Five‐Year International Observational Study

ACR Open Rheumatology, 2023
To evaluate progression from nonradiographic (nr‐) to radiographic axial spondyloarthritis (r‐axSpA) over 5 years in patients with recently diagnosed (≤1 year) axSpA fulfilling the Assessment of SpondyloArthritis international Society (ASAS ...
D. Poddubnyy, J. Sieper, S. Akar, S. Muñoz-Fernández, H. Haibel, T. Diekhoff, M. Protopopov, Elisabeth Altmaier, Fabiana Ganz, Robert D. Inman   +9 more
semanticscholar   +1 more source

Anti‐inflammatory and osteogenic effects of transcutaneous electrical nerve stimulation in knee osteoarthritis rats via the regulation of the intestinal microbiota

Animal Models and Experimental Medicine, EarlyView.
Transcutaneous electrical nerve stimulation (TENS) improved knee osteoarthritis (KOA) in rats by regulating interleukin‐1β (IL‐1β), IL‐6, and IL‐8 expressions and the bone morphogenetic protein 2 (BMP‐2)/transforming growth factor β (TGF‐β) signaling pathway.
Yan Sun, Tong Ma, Ran Chen, Lan Shen, Xun Tang, Zhiqiang Shen, Hongbin Zhao   +6 more
wiley   +1 more source

Relação entre anticorpos anti-Saccharomyces cerevisiae (ASCA) e anti-Helicobacter pylori em pacientes com espondiloartrite axial: um estudo comparativo com doença de Crohn [PDF]

, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Ciências Médicas, Florianópolis, 2013.Introdução: Espondiloartrites (SpA) são doenças musculoesqueléticasinflamatórias crônicas ...
Rodrigues, Igor Kunze
core  

Axial spondyloarthritis: a new disease entity, not necessarily early ankylosing spondylitis.

, 2012
New classification criteria for axial spondyloarthritis have been developed with the goal of increasing sensitivity of criteria for early inflammatory spondyloarthritis. However these criteria substantially increase heterogeneity of the resulting disease
Robinson, P. C., Wordsworth, BP, Reveille, J. D., Brown, Matthew A., Robinson, PC, Wordsworth, B. P., Reveille, JD, Wordsworth, Bryan, Brown, MA   +8 more
core   +1 more source