Results 81 to 90 of about 76,712 (310)

Uveitis in spondyloarthritis [PDF]

Therapeutic Advances in Musculoskeletal Disease, 2020
Uveitis is the most frequent extra-articular manifestation of axial spondyloarthritis (SpA), occurring in up to one-third of the patients. In the majority of patients, uveitis is acute, anterior and unilateral and presents with photosensitivity, sudden onset of pain and blurred vision. Topical steroids are an effective treatment; however, recurrent or
Judith Rademacher, Denis Poddubnyy, Uwe Pleyer   +2 more
openaire   +3 more sources

Mucosal‐Associated Invariant T Cells in Rheumatic Diseases

Arthritis &Rheumatology, EarlyView.
Mucosal‐associated invariant T (MAIT) cells are innate‐like T cells defined by their semi‐invariant T cell receptor and restriction by the major histocompatibility complex class I–related molecule (MR1). These cells are primarily activated by microbial‐derived metabolites presented by MR1 or by cytokines.
Manon Lesturgie‐Talarek, Virginie Gonzalez, Lucie Beaudoin, Noémie Sénot, Corinne Miceli‐Richard, Yannick Allanore, Agnès Lehuen, Jerôme Avouac   +7 more
wiley   +1 more source

Silencing SOCS3 Markedly Deteriorates Spondyloarthritis in Mice Induced by Minicircle DNA Expressing IL23

Frontiers in Immunology, 2018
Objective: Despite extensive studies, the precise mechanism underlying spondyloarthritis, especially ankylosing spondylitis, remains elusive. This study aimed to develop an ideal animal model for an insight into mechanism of spondyloarthritis and ...
Yuhai Chen, Jing Ouyang, Ruoxiang Yan, Mohamed Hassan Maarouf, Mohamed Hassan Maarouf, Mohamed Hassan Maarouf, Xuefei Wang, Xuefei Wang, Biao Chen, Biao Chen, Shasha Liu, Shasha Liu, Jiayue Hu, Guijie Guo, Jing Zhang, Sheng-Ming Dai, Huji Xu, Ji-Long Chen   +17 more
doaj   +1 more source

Spondyloarthritis: Matrix Metalloproteinasesas Biomarkers of Pathogenesis and Response to Tumor Necrosis Factor (TNF) Inhibitors [PDF]

, 2017
The term spondyloarthritis (SpA) is used to describe a group of multifactorial chronic inflammatory diseases characterized by a predisposing genetic background and clinical manifestations typically involving the sacroiliac joint.
Ada Aita, Breban, Daniela Basso, Giovannini, Leonardo Punzi, Maksymowych, Mario Plebani, Massova, Parma, Roberta Ramonda, Stefania Moz, Woo   +11 more
core   +1 more source

Clinical Significance of Gut Microbiota Community Types for Long‐Term Response to Fecal Microbiota Transplantation in Patients With Psoriatic Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Fecal microbiota transplantation (FMT) holds promises as a beneficial supplement to methotrexate in patients with psoriatic arthritis (PsA). We therefore investigated how gut bacterial signatures in patients and donor strain engraftment were associated with long‐term response to FMT.
Panpan Qin, Maja S. Kragsnaes, Dorte K. Holm, Hans Christian Horn, Anna Christine Nilsson, Jens Kjeldsen, Karsten Kristiansen, Torkell Ellingsen   +7 more
wiley   +1 more source

Viral mixed infection complicated by acute hepatitis and allergic toxic dermatitis (clinical case)

Современная ревматология, 2022
Epstein-Barr virus (EBV) belongs to the family of herpesviruses (herpes type 4) and is one of the most common and highly contagious. During the pandemic of a new coronavirus disease, it was found that in patients previously infected with EBV, COVID-19 ...
E. S. Aronova, B. S. Belov, G. I. Gridneva   +2 more
doaj   +1 more source

The prevalence of axial spondyloarthritis in the UK: a cross-sectional cohort study [PDF]

, 2015
Background: Accurate prevalence data are important when interpreting diagnostic tests and planning for the health needs of a population, yet no such data exist for axial spondyloarthritis (axSpA) in the UK.
Alex Macgregor, Andoni Toms, CH Roux, D Poddubnyy, E Collantes, E Tomero, Edward Pinch, F Costantino, J Sieper, JH Kellgren, JS Lawrence, Karl Gaffney, L Hamilton, L Hamilton, L Hoeven Van, Louise Hamilton, M Dougados, M Rojas-Vargas, M Rudwaleit, MR Underwood, R Angelis De, S Linden Van der, SZ Aydin, Victoria Warmington, W Mau   +24 more
core   +1 more source

The Impact of Nonsteroidal Anti‐Inflammatory Drugs on Radiographic Spinal Progression in Patients With Axial Spondyloarthritis: 10‐Year Results From an Inception Cohort

Arthritis &Rheumatology, EarlyView.
Objective This study aims to investigate the impact of nonsteroidal anti‐inflammatory drug (NSAID) intake on radiographic spinal progression in axial spondyloarthritis (axSpA), considering different NSAID types (COX‐2 inhibitors [COX2i] and nonselective NSAIDs [ns‐NSAIDs]) and disease subgroups (radiographic [r‐axSpA] and nonradiographic [nr‐axSpA ...
Murat Torgutalp, Valeria Rios Rodriguez, Fabian Proft, Mikhail Protopopov, Judith Rademacher, Hildrun Haibel, Joachim Sieper, Martin Rudwaleit, Denis Poddubnyy   +8 more
wiley   +1 more source

Biomarkers for successful tapering of a tumor necrosis factor inhibitor in patients with radiographic axial spondyloarthritis: A pilot study

SAGE Open Medicine
Background: Tumor necrosis factor inhibitors are the most widely used biological disease-modifying antirheumatic drugs for radiographic axial spondyloarthritis.
Hong Ki Min, Ji-Yeon Lee
doaj   +1 more source

Changes in serum somatostatin level and its association with calcium metabolism indicators in patients with gastroesophageal reflux disease and spinal injuries of degenerative-dystrophic and inflammatory genesis

Gastroenterologìa, 2022
Background. The study of clinical features, factors and levels of various biologically active substances that may play an important role in the pathogenetic mechanism of gastroesophageal reflux disease (GERD) in combination with degenerative-dystrophic ...
Ye.S. Szircsak, S.A. Tsoka, Ya.F. Filak
doaj   +1 more source