Results 51 to 60 of about 12,688 (213)

Biologic agents in juvenile spondyloarthropathies

Pediatric Rheumatology Online Journal, 2016
The juvenile spondyloarthropathies (JSpA) are a group of related rheumatic diseases characterized by involvement of peripheral large joints, axial joints, and entheses (enthesitis) that begin in the early years of life (prior to 16th birthday).The ...
M. Katsicas, R. Russo
semanticscholar   +1 more source

From Adult to Adolescent: Alignment in Clinical Trials and Outcomes in Axial Spondyloarthritis

Arthritis Care &Research, Accepted Article.
Spondyloarthritis (SpA) is a group of chronic inflammatory diseases encompassing axial and peripheral forms, with up to 20% of patients developing symptoms before age 16. Despite this substantial pediatric burden, treatment options for juvenile‐onset SpA (JSpA), particularly those with axial disease (axJSpA), remain limited.
Pamela F. Weiss, Judith A. Smith, Robert A. Colbert, Erin Treemarcki, Michael H. Weisman, Walter P. Maksymowych, Hermine I. Brunner, for the CARRA, SPARTAN, and PRCSG Advisory Council   +9 more
wiley   +1 more source

A case of Eagle syndrome with a marked elongation of the styloid process; investigating its relation to ankylotic spondylitis

Clinical Case Reports, 2023
Eagle syndrome is characterized by the presence of an abnormally elongated styloid process and has been related to different etiologies, including enthesitis, a known feature of spondyloarthropathies.
Dimitrios Angelou, Nicholas Hope, John Canning, Rosemary Stewart   +3 more
doaj   +1 more source

Identifying Systemic Lupus Erythematosus From Serum Proteomic Profiles Using Machine Learning and Genetic Risk Stratification

Arthritis &Rheumatology, EarlyView.
Objective Proteome‐wide risk models for lupus remain underexplored. We developed classification models to identify lupus from serum proteomic profiles. Methods Patients with lupus and individuals with other autoimmune diseases in the UK Biobank were included.
Mehmet Hocaoǧlu, Jishnu Das, Amr H. Sawalha   +2 more
wiley   +1 more source

Genetics of spondyloarthropathies

, 2013
Spondyloarthropathies are a diverse group of conditions, of which ankylosing spondylitis is the prototypic disease, with shared clinical features, genetic risk factors, and histopathological characteristics.
Matthew Brown
core   +1 more source

DIFFERENTIAL DIAGNOSIS IN AXIAL BACK PAIN AT CHILD [PDF]

Romanian Journal of Pediatrics, 2016
Most cases of back axial pain of the child, are lying on the border between pathology and surgical medical specialties. Continuous pain lasting more than two weeks can be a sign of severe pathologies, imposing the urgent clinical, laboratory and ...
Leo Stati
doaj   +1 more source

T cells, the Next Big Target in Axial Spondyloarthritis?

Arthritis &Rheumatology, EarlyView.
Axial spondyloarthritis (axSpA) is a chronic inflammatory disease characterized by complex immune dysregulation, with T cells playing a central role in its pathogenesis. In this review, we synthesize current knowledge on diverse T cell subsets in axSpA, their pathogenic mechanisms, and emerging therapeutic strategies targeting these cells. We highlight
Mansi K. Aparnathi, Nigil Haroon
wiley   +1 more source

Evidence of Chronic Tusk Trauma and Compensatory Scoliosis in Mammuthus meridionalis from Madonna della Strada (Scoppito, L’Aquila, Italy)

Quaternary
A remarkably well-preserved skeleton of a male Mammuthus meridionalis, approximately 60 years old, from the Early Pleistocene that is housed at the Castle of L’Aquila (Italy) exhibits a fractured left tusk with severe bone erosion of the alveolus and ...
Leonardo Della Salda, Amedeo Cuomo, Franco Antonucci, Silvano Agostini, Maria Adelaide Rossi   +4 more
doaj   +1 more source

Associação entre os níveis séricos de potenciais biomarcadores com a presença de fatores relacionados à atividade clínica e ao mau prognóstico em espondiloartrites The association between serum levels of potential biomarkers with the presence of factors related to the clinical activity and poor prognosis in spondyloarthritis

Revista Brasileira de Reumatologia, 2012
INTRODUÇÃO: Biomarcadores séricos, tradicionalmente associados à atividade inflamatória e mau prognóstico em doenças reumáticas, não apresentam a mesma relação nas espondiloartrites.
John Londono, Maria Consuelo Romero-Sanchez, Viviana Garcia Torres, Wilson A. Bautista, Diego Jaimes Fernandez, Julitte de Avila Quiroga, Rafael Valle-Oñate, Ana María Santos, Juan Francisco Medina   +8 more
doaj   +1 more source

Point‐of‐Care Ultrasound for the Diagnosis of Hip Effusion in Children Presenting to the Emergency Department With Atraumatic Limp or Hip Pain: A Scoping Review

Journal of Ultrasound in Medicine, EarlyView.
This study reviews the evidence for point‐of‐care ultrasound (POCUS) for the detection of hip effusion in children presenting to the emergency department with atraumatic limp or hip pain. A scoping review was conducted using the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses Extension for Scoping Review (PRISMA‐ScR) guideline ...
Nigel Chan, David J. McCreary, Adriana Nedyalkova, Peter J. Snelling   +3 more
wiley   +1 more source