Mucin Glycoprotein Nanoparticles Enable a Selective Antisense Therapy for Oncogenic MicroRNAs
Mucin glycoproteins are turned into nanoparticles by employing synthetic DNA strands, which have a dual function: they stabilize the nanoparticles and act as binding sites for intracellular miRNA‐21. Thus, upon internalization into tumor cells, these mucin nanoparticles can deplete miRNA‐21 from the cytosol, which induces apoptosis in vitro and in vivo.
Ceren Kimna +9 more
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Experimental exposure to climate change scenarios imposed alterations on the morphological traits of sessile and low-motility marine invertebrates. [PDF]
Chatzinikolaou E +3 more
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This review explains how biomaterials and nanoparticles can be used to induce or modulate tertiary lymphoid structures (TLSs), which are ectopic immune hubs that form in nonlymphoid tissues during chronic disease and cancer. By comparing different methods, the article highlights design principles for modeling TLSs or recapitulating specific TLS ...
Shaza Karaman, Mei ElGindi, Jeremy Teo
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A 38-year retained gossypiboma fortuitously diagnosed after suspected ovarian tumor surgery: a case report. [PDF]
Kawahara H +5 more
europepmc +1 more source
A Case of Chronic Expanding Hematoma in the Thoracic Cavity Treated with Transcatheter Arterial Embolization. [PDF]
Higuchi T +9 more
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The chromosomal genome sequence of the carnivorous sponge, <i>Lycopodina hypogea</i> (Vacelet & Boury-Esnault, 1996) (Poecilosclerida: Cladorhizidae) and its associated microbial metagenome sequences. [PDF]
Pérez T +18 more
europepmc +1 more source
Transcriptomic Insights Into the Immune Repertoire of an Antarctic Sponge. [PDF]
Daille LK +3 more
europepmc +1 more source
Cold adaptation and horizontal gene transfer shape Antarctic sponge microbiomes. [PDF]
Manrique-de-la-Cuba MF +3 more
europepmc +1 more source
Pyrimidine-containing natural products: occurrences and biological activities. [PDF]
Yao JN, Zhu Y, Chen HP, Chen Y.
europepmc +1 more source

