Results 41 to 50 of about 359,945 (355)

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Effects of Nitrogen Application at Different Levels by a Sprinkler Fertigation System on Crop Growth and Nitrogen-Use Efficiency of Winter Wheat in the North China Plain

open access: yesPlants
Nitrogen (N) is an essential macronutrient for crop growth; therefore, N deficit can greatly limit crop growth and production. In the North China Plain (NCP), winter wheat (Triticum aestivum L.) is one of the main food crops, and its yield has increased ...
Keke Wang, Haijun Liu, Zhuangzhuang Gao
doaj   +1 more source

Biology and fishery of Florida's commercial sponges [PDF]

open access: yes, 2000
This fact sheet gives information on the biology and commercial value of sponges found in Florida. Five species in Florida are harvested commercially.
Stevely, John, Sweat, Don
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Circular RNAs in the regulation of cardiac hypertrophy

open access: yesMolecular Therapy: Nucleic Acids, 2022
Cardiac hypertrophy is a physiological adaptation to pressure stress that augments or preserves cardiac function. Prolonged hypertrophy can, however, eventually lead to heart failure.
Siyi Wu, Lili Chen, Xiang Zhou
doaj   +1 more source

SUBTITUSI TEPUNG TALAS PADA PEMBUATAN PRODUK BERAGI (Chocolate Sponge Bread, Pizza, Roti Boy) [PDF]

open access: yes, 2012
Proyek Akhir ini bertujuan untuk: (1) memperoleh formula yang tepat pada produk chocolate sponge bread, pizza dan roti boy dengan subtitusi tepung talas, (2) mengetahui teknik pengolahan yang tepat pada produk chocolate sponge bread, pizza dan roti boy ...
RAHMAWATI WAHYU , UTAMI
core  

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Preparation of Hydroxyapatite Scaffold using Luffa Cylindrica Sponge as Template

open access: yesJurnal Rekayasa Kimia & Lingkungan, 2020
Hydroxyapatite (HA) scaffold has been widely applied in the biomedical field especially for bone implants. The purpose of this research is to determine the influence of dispersant addition and stirring time on HA scaffold which formed using gambas ...
Ahmad Fadli   +4 more
doaj   +1 more source

Evaluation of a novel EHR sidecar application to display RA clinical outcomes during clinic visits: results of a stepped‐wedge cluster randomized pragmatic trial

open access: yesArthritis Care &Research, Accepted Article.
Objective We developed a novel EHR sidecar application to visualize key rheumatoid arthritis (RA) outcomes, including disease activity, physical function, and pain, via a patient‐facing graphical interface designed for use during outpatient visits (“RA PRO dashboard”).
Gabriela Schmajuk   +16 more
wiley   +1 more source

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