Results 41 to 50 of about 168,669 (306)

Circular RNAs in the regulation of cardiac hypertrophy

open access: yesMolecular Therapy: Nucleic Acids, 2022
Cardiac hypertrophy is a physiological adaptation to pressure stress that augments or preserves cardiac function. Prolonged hypertrophy can, however, eventually lead to heart failure.
Siyi Wu, Lili Chen, Xiang Zhou
doaj   +1 more source

Sponges

open access: yesDiscovery reports., 1932
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire   +3 more sources

Subtilomycin: A New Lantibiotic from Bacillus subtilis Strain MMA7 Isolated from the Marine Sponge Haliclona simulans [PDF]

open access: yes, 2013
Bacteriocins are attracting increased attention as an alternative to classic antibiotics in the fight against infectious disease and multidrug resistant pathogens.
Rui Chen   +29 more
core   +1 more source

Intensified Rainfall, Growing Floods: Projecting Urban Drainage Challenges in South-Central China Under Climate Change Scenarios

open access: yesApplied Sciences
Global climate change is intensifying extreme rainfall, exacerbating urban flood risks, and undermining the effectiveness of urban stormwater drainage systems (USDS) designed under stationary climate assumptions.
Zhengduo Bao   +4 more
doaj   +1 more source

Preparation of Hydroxyapatite Scaffold using Luffa Cylindrica Sponge as Template

open access: yesJurnal Rekayasa Kimia & Lingkungan, 2020
Hydroxyapatite (HA) scaffold has been widely applied in the biomedical field especially for bone implants. The purpose of this research is to determine the influence of dispersant addition and stirring time on HA scaffold which formed using gambas ...
Ahmad Fadli   +4 more
doaj   +1 more source

Investigations of the Evolved Molecular Basis for Terpenoid Biosynthesis in Marine Sponges. [PDF]

open access: yesAdv Sci (Weinh)
Confirming and extending a previous observation in another Bubarida sponge, genomic and functional analyses of A. cavernosa reveal that sponges retain the mevalonate pathway and employ single α‐domain T1TSs and UbiA‐type TSs for terpenoid biosynthesis. The absence of T1TSs clustering with other biosynthetic genes tentatively suggests, based on limited ...
Chen F   +6 more
europepmc   +2 more sources

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Effects of Nitrogen Application at Different Levels by a Sprinkler Fertigation System on Crop Growth and Nitrogen-Use Efficiency of Winter Wheat in the North China Plain

open access: yesPlants
Nitrogen (N) is an essential macronutrient for crop growth; therefore, N deficit can greatly limit crop growth and production. In the North China Plain (NCP), winter wheat (Triticum aestivum L.) is one of the main food crops, and its yield has increased ...
Keke Wang, Haijun Liu, Zhuangzhuang Gao
doaj   +1 more source

Is an Apple an Orange? A Large Language Model Benchmark for Candidate Term Extraction and Subclass Decisions Against Upper Ontologies in Engineering and Materials Science

open access: yesAdvanced Engineering Materials, EarlyView.
Building machine‐readable vocabularies for materials science is slow, expert‐driven work. This study benchmarks 13 large language models on two of its first steps: finding candidate terms in engineering articles and deciding where they belong in a class hierarchy.
Thomas Bjarsch   +3 more
wiley   +1 more source

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