Results 51 to 60 of about 124,079 (304)
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Spontaneous use of focused-distraction decreases intrusive thoughts
Journal of Human Environmental Studies, 2012 Previous research has reported that people sometimes try to concentrate their attention on something else to suppress unwanted thoughts. This strategy is called focused-distraction.
Yosuke Hattori, Jun Kawaguchi
doaj +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Nature Prescribes Laws to Humans: The Ziran of the Myriad Things in Early Daoism
Religions, 2023 This essay examines the nature of things in early Daoism via the lens of comparative philosophy. Daoism uses ziran 自然 (spontaneity) to express the nature of things.
Jing Liu
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Murmurations, 2017 Stories from everyday life move and provide inspiration to systemic practitioners while at the same time can teach us important lessons about complex relational movements and improvised coordinations. If surprises don't surprise us and tight rope walking
Joanna Michopoulou
doaj +1 more source
Zhuang Zi and the Education of the Emotions [PDF]
, 2018 This paper examines and defends a conception of the education of emotions found in the Zhuang-Zi. I begin by exploring four principal features of Zhuang Zi’s philosophy as it relates to the emotions: his epistemological perspectivism, his view of the ...
MORGAN, Jeffrey
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
The Realization of Casual Conversation Features of EFL Learners
J-SHMIC: Journal of English for Academic, 2020 This study was descriptive qualitative, which aimed at explaining the casual conversation features between two learners and its functions in terms of negotiation meaning, spontaneity, interpersonality, and interactivity.
Andi Tenry Lawangen Aspat Colle
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The epistemology of Schelling's philosophy of nature [PDF]
, 2017 The philosophy of nature operates as one complete and systematic aspect of Schelling’s philosophy in the years 1797-1801 and as complement to Schelling’s transcendental philosophy at this time.
Fisher, Naomi
core