Results 91 to 100 of about 3,297,974 (375)
Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source
Ligelizumab for Chronic Spontaneous Urticaria.
New England Journal of Medicine, 2019 BACKGROUND In the majority of patients with chronic spontaneous urticaria, most currently available therapies do not result in complete symptom control. Ligelizumab is a next-generation high-affinity humanized monoclonal anti-IgE antibody.
M. Maurer +26 more
semanticscholar +1 more source
Quasiclassical Theory of Spontaneous Currents at Surfaces and Interfaces of d-Wave Superconductors [PDF]
, 2002 We investigate the properties of spontaneous currents generated at surfaces and interfaces of d-wave superconductors using the self-consistent quasiclassical Eilenberger equations.
A.M. Zagoskin +53 more
core +1 more source
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
A zero-mode mechanism for spontaneous symmetry breaking in a turbulent von K\'arm\'an flow [PDF]
, 2014 We suggest that the dynamical spontaneous symmetry breaking reported in a turbulent swirling flow at $Re=40~000$ by Cortet et al., Phys. Rev. Lett., 105, 214501 (2010) can be described through a continuous one parameter family transformation (amounting ...
Daviaud, François +2 more
core +4 more sources
FEBS Open Bio, EarlyView.We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang +9 more
wiley +1 more source
The neuronal basis of human creativity
Frontiers in Human NeuroscienceHuman creativity is a powerful cognitive ability underlying all uniquely human cultural and scientific advancement. However, the neuronal basis of this creative ability is unknown. Here, I propose that slow, spontaneous fluctuations in neuronal activity,
Rafael Malach
doaj +1 more source
Reliability of "Google" for obtaining medical information
Indian Journal of Ophthalmology, 2015 Internet is used by many patients to obtain relevant medical information. We assessed the impact of "Google" search on the knowledge of the parents whose ward suffered from squint.
Mihir Kothari, Samita Moolani
doaj +1 more source