Results 101 to 110 of about 1,493,152 (313)
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Examining the contributions of automatic speech transcriptions and metadata sources for searching spontaneous conversational speech [PDF]
, 2007 The searching spontaneous speech can be enhanced by combining automatic speech transcriptions with semantically related metadata. An important question is what can be expected from search of such transcriptions and different sources of related metadata
Zhang, Ke +3 more
core +2 more sources
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Spontaneous Air Leak Syndromes in COVID-19: A Retrospective Analysis of 124 Patients [PDF]
Journal of Cardio-Thoracic MedicineIntroduction: Air leak syndromes, including pneumothorax and pneumomediastinum, have emerged as important complications in patients with COVID-19, often occurring even in the absence of invasive respiratory support.
Mithat Fazlıoğlu +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler +3 more
wiley +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Rapid entrainment to spontaneous speech: A comparison of oscillator models [PDF]
, 2012 Inden B, Malisz Z, Wagner P, Wachsmuth I. Rapid entrainment to spontaneous speech: A comparison of oscillator models. In: Miyake N, Peebles D, Cooper RP, eds. Proceedings of the 34th Annual Conference of the Cognitive Science Society.
Wagner, Petra ; https://orcid.org/ +6 more
core
The neuronal basis of human creativity
Frontiers in Human NeuroscienceHuman creativity is a powerful cognitive ability underlying all uniquely human cultural and scientific advancement. However, the neuronal basis of this creative ability is unknown. Here, I propose that slow, spontaneous fluctuations in neuronal activity,
Rafael Malach
doaj +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
NIOSH updates spontaneous combustion assessment software [PDF]
"Objective: To update the current SPONCOM software to SponCom 2.0 with a Windows-based platform, using tabs and easy-to-navigate screens for entering or selecting data.
core +1 more source