Results 121 to 130 of about 1,493,152 (313)
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez +4 more
wiley +1 more source
Spontaneous pneumopericardium [PDF]
A S, Iskander, E C, Schick, A B, Levin
openaire +2 more sources
Prediction and Realisation of Conversational Characteristics by Utilising Spontaneous Speech for Unit Selection [PDF]
Unit selection speech synthesis has reached high levels of naturalness and intelligibility for neutral read aloud speech. However, synthetic speech generated using neutral read aloud data lacks all the attitude, intention and spontaneity associated with ...
Traum, David +5 more
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Cell surface CD11c as a neutrophil aging marker molecule
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
Laparoscopic Management of Boerhaave Syndrome: Case Series and Narrative Review
Boerhaave syndrome, or spontaneous rupture of the esophageal wall, is a rare condition that occurs after a violent increase in intraesophageal pressure associated with negative intrathoracic pressure after forceful vomiting or retching.
Floris Cristian Stănculea +8 more
doaj +1 more source
Spontaneous pneumomediastinum [PDF]
Kei, Kira +3 more
openaire +2 more sources
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli +2 more
wiley +1 more source
At head of title, v.3-4; Mines Dept.v.1, title reads: ... First report; v.2, ... Minutes of evidence.At head of title: Home Office.
Great Britain. Committee on Spontaneous Combustion of Coal in Mines.
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