Results 121 to 130 of about 1,493,152 (313)

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

open access: yesFEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez   +4 more
wiley   +1 more source

Spontaneous pneumopericardium [PDF]

open access: yesHeart, 2003
A S, Iskander, E C, Schick, A B, Levin
openaire   +2 more sources

Prediction and Realisation of Conversational Characteristics by Utilising Spontaneous Speech for Unit Selection [PDF]

open access: yes, 2010
Unit selection speech synthesis has reached high levels of naturalness and intelligibility for neutral read aloud speech. However, synthetic speech generated using neutral read aloud data lacks all the attitude, intention and spontaneity associated with ...
Traum, David   +5 more
core  

Cell surface CD11c as a neutrophil aging marker molecule

open access: yesFEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki   +5 more
wiley   +1 more source

Laparoscopic Management of Boerhaave Syndrome: Case Series and Narrative Review

open access: yesLife
Boerhaave syndrome, or spontaneous rupture of the esophageal wall, is a rare condition that occurs after a violent increase in intraesophageal pressure associated with negative intrathoracic pressure after forceful vomiting or retching.
Floris Cristian Stănculea   +8 more
doaj   +1 more source

Spontaneous pneumomediastinum [PDF]

open access: yesBMJ Case Reports, 2016
Kei, Kira   +3 more
openaire   +2 more sources

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

open access: yesFEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli   +2 more
wiley   +1 more source

Report of the Departmental Committee on Spontaneous Combustion of Coal in Mines. Minutes of evidence ... (1st to 26th days) with index.

open access: yes, 1916
At head of title, v.3-4; Mines Dept.v.1, title reads: ... First report; v.2, ... Minutes of evidence.At head of title: Home Office.
Great Britain. Committee on Spontaneous Combustion of Coal in Mines.
core  

Home - About - Disclaimer - Privacy