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Drugs in Development for Chronic Spontaneous Urticaria

Journal of Drugs in Dermatology, 2023
Chronic spontaneous urticaria (CSU) is a debilitating disease for which many patients are inadequately treated. However, recent advancements in our understanding of the disease pathophysiology allow us to develop therapies that are more effective for CSU.
William, Nguyen   +2 more
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Spontaneous Development of Moral Concepts

Human Development, 2009
It is argued that moral competence is more difficult to attain than scientific competence owing to the difficulty of learning moral language. Language comprehension is seen to play a central role in conceptual development; that moral language is difficult to learn results in a common deficiency in moral conceptual development.
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ADRENALINE AND THE DEVELOPMENT OF SPONTANEOUS HYPERTENSION IN RATS

Journal of Autonomic Pharmacology, 1985
The effects of chronic alterations in plasma adrenaline levels, on the development of a raised blood pressure in young spontaneously hypertensive (SHR) rats, have been investigated. Bilateral adrenal demedullation (at 4 weeks) significantly reduced plasma adrenaline levels and attenuated the development of hypertension.
K R, Borkowski, P, Quinn
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Spontaneous Pubertal Development in Turner's Syndrome

Journal of Clinical Endocrinology & Metabolism, 1997
The incidence of spontaneous puberty in Turner's syndrome is reported to be between 5-10% and, more recently in some series, as high as 20%. In an Italian retrospective multicenter study, of 522 patients older than 12 yr with Turner's syndrome, 84 patients (16, 1%) presented spontaneous pubertal development with menarche that occurred at a ...
PASQUINO, Anna Maria   +4 more
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Contribution of the amygdala to the development of spontaneous hypertension

Brain Research, 1982
Abstract The role of the central amygdaloid nucleus in the development and maintenance of high blood pressure was investigated in the spontaneously hypertensive rat (SHR). Bilateral lesions in the central nucleus in prehypertensive rats inhibited the development of the high blood pressure, whereas larger amygdaloid lesions that included the central ...
T M, Galeno   +4 more
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Planning and Spontaneity in Economic Development

Eastern European Economics, 1986
(1986). Planning and Spontaneity in Economic Development. Eastern European Economics: Vol. 24, No. 3, pp. 24-34.
Stefan Marciniak, Zofia Zawadzka
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The Spontaneous Development of Biology from Chemistry

Astrobiology, 2008
Biology arose as a spontaneous development from the chemistry of the early Earth by Free Energy-driven processes that occurred in common environments involving significant populations of systems. Molecular imprinting to matrices is capable of catalysis of polymer formation and reproduction that, in association with self-assembled membranes, could lead ...
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Control of spontaneous activity during development

Journal of Neurobiology, 1998
Electrical activity participates in the development of the nervous system and comes in two general forms. Use-dependent or experience-driven activity occurs relatively late in development, and is important in events of terminal nervous system differentiation, such as stabilization of synaptic connections. Earlier in development, activity is spontaneous,
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Development of microvascular rarefaction in the spontaneously hypertensive rat

American Journal of Physiology-Heart and Circulatory Physiology, 1982
Using stereological methods in vivo, we have investigated the rarefaction of arterioles and capillaries in male spontaneously hypertensive rats (SHR) and the Wistar-Kyoto controls (WKY) at 6-8, 12-14, and 16-18 wk of age. Under chloralose-urethan anesthesia, the gracilis muscle was isolated for microscopic observation.
R L, Prewitt, I I, Chen, R, Dowell
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Spontaneity Theory of Child Development

Sociometry, 1944
J. L. Moreno, Florence B. Moreno
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