Results 1 to 10 of about 630,990 (118)

Embedding stochastic dynamics of the environment in spontaneous activity by prediction-based plasticity [PDF]

eLife
The brain learns an internal model of the environment through sensory experiences, which is essential for high-level cognitive processes. Recent studies show that spontaneous activity reflects such a learned internal model. Although computational studies
Toshitake Asabuki, Claudia Clopath
doaj   +2 more sources

Circuit mechanisms underlying embryonic retinal waves

eLife, 2023
Spontaneous activity is a hallmark of developing neural systems. In the retina, spontaneous activity comes in the form of retinal waves, comprised of three stages persisting from embryonic day 16 (E16) to eye opening at postnatal day 14 (P14).
Christiane Voufo, Andy Quaen Chen, Benjamin E Smith, Rongshan Yan, Marla B Feller, Alexandre Tiriac   +5 more
doaj   +1 more source

An In Vitro Assessment Method for Chemotherapy-Induced Peripheral Neurotoxicity Caused by Anti-Cancer Drugs Based on Electrical Measurement of Impedance Value and Spontaneous Activity

Pharmaceutics, 2023
Chemotherapy-induced peripheral neurotoxicity (CIPN) is a major adverse event of anti-cancer drugs, which still lack standardized measurement and treatment methods.
Xiaobo Han, Naoki Matsuda, Yuto Ishibashi, Mikako Shibata, Ikuro Suzuki   +4 more
doaj   +1 more source

Altered Spontaneous Brain Activity Patterns and Functional Connectivity in Adults With Intermittent Exotropia: A Resting-State fMRI Study

Frontiers in Neuroscience, 2021
The purpose of this study is to investigate brain functional changes in patients with intermittent exotropia (IXT) by analyzing the amplitude of low-frequency fluctuation (ALFF) of brain activity and functional connectivity (FC) using resting-state ...
Xueying He, Jie Hong, Qian Wang, Yanan Guo, Ting Li, Xiaoxia Qu, Jing Liu, Wei Li, Lirong Zhang, Jing Fu, Zhaohui Liu   +10 more
doaj   +1 more source

Neuronal Cultures: Exploring Biophysics, Complex Systems, and Medicine in a Dish

Biophysica, 2023
Neuronal cultures are one of the most important experimental models in modern interdisciplinary neuroscience, allowing to investigate in a control environment the emergence of complex behavior from an ensemble of interconnected neurons.
Jordi Soriano
doaj   +1 more source

Spontaneous neuronal activity in developing neocortical networks: from single cells to large-scale cortical interactions

Frontiers in Neural Circuits, 2016
Neuronal activity has been shown to be essential for the proper formation of neuronal circuits, affecting developmental processes like neurogenesis, migration, programmed cell death, cellular differentiation, formation of local and long-range axonal ...
Heiko J. Luhmann, Anne eSinning, Jenq-Wei eYang, Vicente eReyes-Puerta, Maik eStuettgen, Sergei eKirischuk, Werner eKilb   +6 more
doaj   +1 more source

An in vivo Calcium Imaging Approach for the Identification of Cell-Type Specific Patterns in the Developing Cortex

Frontiers in Neural Circuits, 2021
Neuronal activity profoundly shapes the maturation of developing neurons. However, technical limitations have hampered the ability to capture the progression of activity patterns in genetically defined neuronal populations.
Alicia Che, Natalia V. De Marco García
doaj   +1 more source

Laminar distribution of phase-amplitude coupling of spontaneous current sources and sinks

Frontiers in Neuroscience, 2015
Although resting-state functional connectivity is a commonly used neuroimaging paradigm, the underlying mechanisms remain unknown. Thalamo-cortical and cortico-cortical circuits generate oscillations at different frequencies during spontaneous activity ...
Roberto C Sotero, Alekasandra Beata Bortel, Shmuel eNaaman, Victor Mihai Mocanu, Pascal eKropf, Martin eVilleneuve, Amir eShmuel   +6 more
doaj   +1 more source

Cortico-cortical communication dynamics

Frontiers in Systems Neuroscience, 2014
IIn principle, cortico-cortical communication dynamics is simple: neurons in one cortical area communicate by sending action potentials that release glutamate and excite their target neurons in other cortical areas.
Per E Roland, Claus C Hilgetag, Gustavo eDeco   +2 more
doaj   +1 more source

Barbed channels enhance unidirectional connectivity between neuronal networks cultured on multi electrode arrays.

Frontiers in Neuroscience, 2015
Cultured neurons on multi electrode arrays (MEAs) have been widely used to study various as-pects of neuronal (network) functioning. A possible drawback of this approach is the lack of structure in these networks.
Joost eLe Feber, Wybren ePostma, Eddy ede Weerd, Marcel eWeusthof, Wim L C Rutten   +4 more
doaj   +1 more source